The synthesis of (±)-aminoglutethimide via vicarious nucleophilic aromatic substitution of hydrogen

被引：10
|
作者：
Bushell, SM [1 ]
Crump, JP [1 ]
Lawrence, NJ [1 ]
Pineau, G [1 ]
机构：
[1] Univ Manchester, Inst Sci & Technol, Dept Chem, Manchester M60 1QD, Lancs, England
来源：
TETRAHEDRON | 1998年 / 54卷 / 10期
关键词：
D O I：
10.1016/S0040-4020(97)10436-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of aminoglutethimide via a one-pot coupling of nitrobenzene, ethyl 2-chlorobutyrate and 3-bromopropionitrile has been achieved via a process involving sequential vicarious nucleophilic aromatic substitution and alkylation. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2269 / 2274
页数：6
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