The synthesis of (±)-aminoglutethimide via vicarious nucleophilic aromatic substitution of hydrogen

被引：10

作者：

Bushell, SM ^{[1
]}

Crump, JP ^{[1
]}

Lawrence, NJ ^{[1
]}

Pineau, G ^{[1
]}

机构：

[1] Univ Manchester, Inst Sci & Technol, Dept Chem, Manchester M60 1QD, Lancs, England

来源：

TETRAHEDRON | 1998年 / 54卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(97)10436-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of aminoglutethimide via a one-pot coupling of nitrobenzene, ethyl 2-chlorobutyrate and 3-bromopropionitrile has been achieved via a process involving sequential vicarious nucleophilic aromatic substitution and alkylation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2269 / 2274

页数：6

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