Prognostic role of neutrophil lymphocyte ratio in patients with spontaneous intracerebral hemorrhage

被引：15

作者：

Zhang, Jing ^{[1
]}

Cai, Linrui ^{[2
]}

Song, Yanlin ^{[3
]}

Shan, Baoyin ^{[1
]}

He, Min ^{[1
]}

Ren, Qingqing ^{[1
]}

Chen, Chaoyue ^{[1
]}

Liu, Zhiyong ^{[1
]}

Zeng, Yunhui ^{[1
]}

Xu, Jianguo ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp, Dept Neurosurg, Chengdu 610041, Sichuan, Peoples R China

[2] Sichuan Univ, West China Univ Hosp 2, Natl Drug Clin Trial Inst, Chengdu 610041, Sichuan, Peoples R China

[3] Sichuan Univ, West China Hosp, West China Sch Med, Chengdu 610041, Sichuan, Peoples R China

来源：

ONCOTARGET | 2017年 / 8卷 / 44期

关键词：

neutrophil lymphocyte ratio; intracerebral hemorrhage; prognosis; outcome; CEREBRAL-HEMORRHAGE; BLOOD-PRESSURE; PREDICTS; MORTALITY; VOLUME; SCALE; COUNT; SIGN;

D O I：

10.18632/oncotarget.20776

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The aim of this study was to evaluate the prognostic role of neutrophil lymphocyte ratio (NLR) in patients with spontaneous intracerebral hemorrhage (ICH). PubMed, EMBASE, Web of Knowledge, Cochrane Library and China National Knowledge Infrastructure were searched for potentially relevant literature. The study and patient characteristics were extracted. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to estimate the prognostic role of NLR in patients with ICH. Poor functional outcome was defined as modified Rankin Scale >= 3. Four studies with 1,720 patients were included. The pooled OR of higher NLR for poor functional outcome at 3 months was 2.74 (95% CI, 1.33-5.65). The pooled OR of higher NLR for death at 3 months was 1.58 (95% CI, 0.44-5.68). Subgroup analysis and sensitivity analysis were also performed. Publication bias was not present. In conclusion, for patients with ICH, higher NLR was associated with poorer functional outcome at 3 months, while higher NLR was not associated with higher risk of death at 3 months.

引用

页码：77752 / 77760

页数：9

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