The Structure-Antioxidant Activity Relationship of Ferulates

被引:38
作者
Karamac, Magdalena [1 ]
Koleva, Lidiya [2 ]
Kancheva, Vessela D. [2 ]
Amarowicz, Ryszard [1 ]
机构
[1] Polish Acad Sci, Inst Anim Reprod & Food Res, Dept Chem & Phys Properties Food, Tuwima 10, PL-10748 Olsztyn, Poland
[2] Bulgarian Acad Sci, Inst Organ Chem, Ctr Phytochem, Lipid Chem Dept, BU-1113 Sofia, Bulgaria
来源
MOLECULES | 2017年 / 22卷 / 04期
关键词
ferulates; structure; antioxidant activity; 2,2 '-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS); ferric-reducing antioxidant power (FRAP); lipid oxidation; RADICAL SCAVENGING ACTIVITY; FERULIC ACID-DERIVATIVES; PHENOLIC-ACIDS; HYDROXYL; CARYOPSES; BERRIES; PEROXYL; WHEAT; RYE;
D O I
10.3390/molecules22040527
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The antioxidant activity of ferulic acid (1), iso-ferulic acid (2), coniferyl aldehyde (3), methyl ferulate (4), and ethyl ferulate (5) were investigated using 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and ferric-reducing antioxidant power (FRAP) assays and autoxidation of triacylglycerols of commercially available sunflower oil (TGSO). The compounds tested for ability to scavenge ABTS radical cations was in the order of ferulic acid > coniferyl aldehyde approximate to iso-ferulic acid > ethyl ferulate approximate to methyl ferulate. The results of the FRAP assay for ferulic acid, iso-ferulic acid, and coniferyl aldehyde were similar to and higher than those of methyl ferulate and ethyl ferulate. In the lipid system, iso-ferulic acid showed weak antioxidant activity. The other ferulates exhibited much stronger, yet similar, activities.
引用
收藏
页数:8
相关论文
共 38 条
  • [21] Ferulic acid: Pharmacological and toxicological aspects
    Mancuso, Cesare
    Santangelo, Rosaria
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2014, 65 : 185 - 195
  • [22] Contents of phenolic acids, alkyl- and alkenylresorcinols, and avenanthramides in commercial grain products
    Mattila, P
    Pihlava, JM
    Hellström, J
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (21) : 8290 - 8295
  • [23] Phenolic acids in berries, fruits, and beverages
    Mattila, Pirjo
    Hellstrom, Jarkko
    Torronen, Riitta
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (19) : 7193 - 7199
  • [24] Mori H, 1999, ANTICANCER RES, V19, P3775
  • [25] Ethyl Ferulate, a Component with Anti-Inflammatory Properties for Emulsion-Based Creams
    Nazare, Ana C.
    de Faria, Carolina M. Q. G.
    Chiari, Bruna G.
    Petronio, Maicon S.
    Regasini, Luis O.
    Silva, Dulce H. S.
    Correa, Marcos A.
    Isaac, Vera L. B.
    da Fonseca, Luiz M.
    Ximenes, Valdecir F.
    [J]. MOLECULES, 2014, 19 (06): : 8124 - 8139
  • [26] Structure-antioxidant activity relationship of ferulic acid derivatives: Effect of carbon side chain characteristic groups
    Nenadis, N
    Zhang, HY
    Tsimidou, MZ
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (07) : 1874 - 1879
  • [27] Antioxidant Activity of Phenolic Acids and Their Metabolites: Synthesis and Antioxidant Properties of the Sulfate Derivatives of Ferulic and Caffeic Acids and of the Acyl Glucuronide of Ferulic Acid
    Piazzon, A.
    Vrhovsek, U.
    Masuero, D.
    Mattivi, F.
    Mandoj, F.
    Nardini, M.
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (50) : 12312 - 12323
  • [28] Antioxidant activity applying an improved ABTS radical cation decolorization assay
    Re, R
    Pellegrini, N
    Proteggente, A
    Pannala, A
    Yang, M
    Rice-Evans, C
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1999, 26 (9-10) : 1231 - 1237
  • [29] Structure-antioxidant activity relationships of flavonoids and phenolic acids
    RiceEvans, CA
    Miller, NJ
    Paganga, G
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (07) : 933 - 956
  • [30] PHENOLIC ANTIOXIDANTS
    SHAHIDI, F
    JANITHA, PK
    WANASUNDARA, PD
    [J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 1992, 32 (01) : 67 - 103