Rational design and biomedical applications of DNA-functionalized upconversion nanoparticles

被引：33

作者：

Liu, Xinwen ^{[1
]}

Liu, Meng ^{[1
]}

Chen, Jiajia ^{[1
]}

Li, Zhihao ^{[1
]}

Yuan, Quan ^{[1
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Minist Educ, Key Lab Analyt Chem Biol & Med, Wuhan 430072, Hubei, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2018年 / 29卷 / 09期

基金：

中国国家自然科学基金;

关键词：

Lanthanide-doped upconversion; nanoparticles; DNA; Biosensor; Bioimaging; Disease therapy; RESONANCE ENERGY-TRANSFER; PHOTON-UPCONVERTING NANOPARTICLES; SENSITIVE DETECTION; TRANSFER BIOSENSOR; DRUG-DELIVERY; LUMINESCENT NANOPARTICLES; TRANSFER APTASENSOR; LIVING CELLS; ULTRASENSITIVE DETECTION; PHOTODYNAMIC THERAPY;

D O I：

10.1016/j.cclet.2018.03.004

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lanthanide-doped upconversion nanoparticles (UCNPs) offer unique advantages in term of low autofluorescence, high signal-to-noise ratio and deep tissue penetration, and have attracted considerable attention in biomedical applications. DNA, beyond the properties of self-assembly, also exhibits multiple functions such as molecular recognition, drug loading capacity and therapeutic effect. In this regard, the combination of UCNPs and DNA offers a promising and powerful platform for potential applications in biosensing, bioimaging and disease therapy. In this review, we mainly introduce recent progresses of DNA-functionalized upconversion materials, providing an overview of the design and applications in biosensing, bioimaging and therapy. The challenges and future perspectives are also discussed, aiming to promote their applications in material science and biomedicine. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

引用

页码：1321 / 1332

页数：12

共 122 条

[51] A photoluminescent biosensor based on long-range self-assembled DNA cascades and upconversion nanoparticles for the detection of breast cancer-associated circulating microRNA in serum samples [J].

Lan, Jianming ;

Wen, Fadi ;

Fu, Fangmeng ;

Zhang, Xi ;

Cai, Shuxian ;

Liu, Zhijing ;

Wu, Dongzhi ;

Li, Chunyan ;

Chen, JingHua ;

Wang, Chuan .

RSC ADVANCES, 2015, 5 (23) :18008-18012

[52] Enhancement of the Upconversion Emission by Visible-to-Near-Infrared Fluorescent Graphene Quantum Dots for miRNA Detection [J].

Laurenti, Marco ;

Paez-Perez, Miguel ;

Algarra, Manuel ;

Alonso-Cristobal, Paulino ;

Lopez-Cabarcos, Enrique ;

Mendez-Gonzalez, Diego ;

Rubio-Retama, Jorge .

ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (20) :12644-12651

[53] Regiospecific Hetero-Assembly of DNA-Functionalized Plasmonic Upconversion Superstructures [J].

Li, Le-Le ;

Lu, Yi .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (16) :5272-5275

[54] An Exceptionally Simple Strategy for DNA-Functionalized Up-Conversion Nanoparticles as Biocompatible Agents for Nanoassembly, DNA Delivery, and Imaging [J].

Li, Le-Le ;

Wu, Peiwen ;

Hwang, Kevin ;

Lu, Yi .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (07) :2411-2414

[55] Dual-Mode Ultrasensitive Quantification of MicroRNA in Living Cells by Chiroplasmonic Nanopyramids Self-Assembled from Gold and Upconversion Nanoparticles [J].

Li, Si ;

Xu, Liguang ;

Ma, Wei ;

Wu, Xiaoling ;

Sun, Maozhong ;

Kuang, Hua ;

Wang, Libing ;

Kotov, Nicholas A. ;

Xu, Chuanlai .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (01) :306-312

[56] Amorphizing of Au Nanoparticles by CeOx-RGO Hybrid Support towards Highly Efficient Electrocatalyst for N2 Reduction under Ambient Conditions [J].

Li, Si-Jia ;

Bao, Di ;

Shi, Miao-Miao ;

Wulan, Ba-Ri ;

Yan, Jun-Min ;

Jiang, Qing .

ADVANCED MATERIALS, 2017, 29 (33)

[57] Study on the Adsorption Mechanism of DNA with Mesoporous Silica Nanoparticles in Aqueous Solution [J].

Li, Xu ;

Zhang, Jixi ;

Gu, Hongchen .

LANGMUIR, 2012, 28 (05) :2827-2834

[58] Fluorescence resonance energy transfer aptasensor for platelet-derived growth factor detection based on upconversion nanoparticles in 30% blood serum [J].

Lin, Fanbo ;

Yin, Bangda ;

Li, Chengzhi ;

Deng, Jianhui ;

Fan, Xiaoyu ;

Yi, Yinhui ;

Liu, Chang ;

Li, Haitao ;

Zhang, Youyu ;

Yao, Shouzhuo .

ANALYTICAL METHODS, 2013, 5 (03) :699-704

[59] A Two-Dimensional Biodegradable Niobium Carbide (MXene) for Photothermal Tumor Eradication in NIR-I and NIR-II Biowindows [J].

Lin, Han ;

Gao, Shanshan ;

Dai, Chen ;

Chen, Yu ;

Shi, Jianlin .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (45) :16235-16247

[60] Facial Layer-by-Layer Engineering of Upconversion Nanoparticles for Gene Delivery: Near-Infrared-Initiated Fluorescence Resonance Energy Transfer Tracking and Overcoming Drug Resistance in Ovarian Cancer [J].

Lin, Min ;

Gao, Yan ;

Diefenbach, Thomas J. ;

Shen, Jacson K. ;

Hornicek, Francis J. ;

Park, Yong Il ;

Xu, Feng ;

Lu, Tian Jian ;

Amiji, Mansoor ;

Duan, Zhenfeng .

ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (09) :7941-7949

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