An Arabidopsis haplotype map takes root

被引:25
作者
Buckler, Edward [1 ]
Gore, Michael
机构
[1] USDA, ARS, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Plant Breeding & Genet, Ithaca, NY 14853 USA
关键词
D O I
10.1038/ng0907-1056
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The report of a haplotype map for the selfing plant Arabidopsis thaliana has uncovered numerous major- effect polymorphisms and rapid linkage disequilibrium decay. This work lays the foundation for genome- wide association studies at near- gene- level resolution in a model organism possessing substantial functional diversity and extensive community resources.
引用
收藏
页码:1056 / 1057
页数:3
相关论文
共 13 条
[1]   A haplotype map of the human genome [J].
Altshuler, D ;
Brooks, LD ;
Chakravarti, A ;
Collins, FS ;
Daly, MJ ;
Donnelly, P ;
Gibbs, RA ;
Belmont, JW ;
Boudreau, A ;
Leal, SM ;
Hardenbol, P ;
Pasternak, S ;
Wheeler, DA ;
Willis, TD ;
Yu, FL ;
Yang, HM ;
Zeng, CQ ;
Gao, Y ;
Hu, HR ;
Hu, WT ;
Li, CH ;
Lin, W ;
Liu, SQ ;
Pan, H ;
Tang, XL ;
Wang, J ;
Wang, W ;
Yu, J ;
Zhang, B ;
Zhang, QR ;
Zhao, HB ;
Zhao, H ;
Zhou, J ;
Gabriel, SB ;
Barry, R ;
Blumenstiel, B ;
Camargo, A ;
Defelice, M ;
Faggart, M ;
Goyette, M ;
Gupta, S ;
Moore, J ;
Nguyen, H ;
Onofrio, RC ;
Parkin, M ;
Roy, J ;
Stahl, E ;
Winchester, E ;
Ziaugra, L ;
Shen, Y .
NATURE, 2005, 437 (7063) :1299-1320
[2]   Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana [J].
Clark, Richard M. ;
Schweikert, Gabriele ;
Toomajian, Christopher ;
Ossowski, Stephan ;
Zeller, Georg ;
Shinn, Paul ;
Warthmann, Norman ;
Hu, Tina T. ;
Fu, Glenn ;
Hinds, David A. ;
Chen, Huaming ;
Frazer, Kelly A. ;
Huson, Daniel H. ;
Schoelkopf, Bernhard ;
Nordborg, Magnus ;
Raetsch, Gunnar ;
Ecker, Joseph R. ;
Weigel, Detlef .
SCIENCE, 2007, 317 (5836) :338-342
[3]   Intraspecific violation of genetic colinearity and its implications in maize [J].
Fu, HH ;
Dooner, HK .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (14) :9573-9578
[4]   Challenges of detecting directional selection after a bottleneck:: Lessons from Sorghum bicolor [J].
Hamblin, Martha T. ;
Casa, Alexandra M. ;
Sun, Hong ;
Murray, Seth C. ;
Paterson, Andrew H. ;
Aquadro, Charles F. ;
Kresovich, Stephen .
GENETICS, 2006, 173 (02) :953-964
[5]   Whole-genome patterns of common DNA variation in three human populations [J].
Hinds, DA ;
Stuve, LL ;
Nilsen, GB ;
Halperin, E ;
Eskin, E ;
Ballinger, DG ;
Frazer, KA ;
Cox, DR .
SCIENCE, 2005, 307 (5712) :1072-1079
[6]   Highly variable patterns of linkage disequilibrium in multiple soybean populations [J].
Hyten, David L. ;
Choi, Ik-Young ;
Song, Qijian ;
Shoemaker, Randy C. ;
Nelson, Randall L. ;
Costa, Jose M. ;
Specht, James E. ;
Cregan, Perry B. .
GENETICS, 2007, 175 (04) :1937-1944
[7]   Recombination and linkage disequilibrium in Arabidopsis thaliana [J].
Kim, Sung ;
Plagnol, Vincent ;
Hu, Tina T. ;
Toomajian, Christopher ;
Clark, Richard M. ;
Ossowski, Stephan ;
Ecker, Joseph R. ;
Weigel, Detlef ;
Nordborg, Magnus .
NATURE GENETICS, 2007, 39 (09) :1151-1155
[8]   The pattern of polymorphism in Arabidopsis thaliana [J].
Nordborg, M ;
Hu, TT ;
Ishino, Y ;
Jhaveri, J ;
Toomajian, C ;
Zheng, HG ;
Bakker, E ;
Calabrese, P ;
Gladstone, J ;
Goyal, R ;
Jakobsson, M ;
Kim, S ;
Morozov, Y ;
Padhukasahasram, B ;
Plagnol, V ;
Rosenberg, NA ;
Shah, C ;
Wall, JD ;
Wang, J ;
Zhao, KY ;
Kalbfleisch, T ;
Schulz, V ;
Kreitman, M ;
Bergelson, J .
PLOS BIOLOGY, 2005, 3 (07) :1289-1299
[9]   The extent of linkage disequilibrium in Arabidopsis thaliana [J].
Nordborg, M ;
Borevitz, JO ;
Bergelson, J ;
Berry, CC ;
Chory, J ;
Hagenblad, J ;
Kreitman, M ;
Maloof, JN ;
Noyes, T ;
Oefner, PJ ;
Stahl, EA ;
Weigel, D .
NATURE GENETICS, 2002, 30 (02) :190-193
[10]  
Nordborg M, 2000, GENETICS, V154, P923