Staphylococcus aureus nasal colonization among HIV-infected adults in Botswana: prevalence and risk factors

被引:10
作者
Reid, Michael J. A. [1 ]
Steenhoff, Andrew P. [2 ,3 ]
Mannathoko, Naledi [4 ]
Muthoga, Charles [2 ]
McHugh, Erin [5 ]
Brown, Eric L. [5 ]
Fischer, Rebecca S. B. [5 ,6 ]
机构
[1] Univ Calif San Francisco, Div Infect Dis, 513 Parnassus Ave,S380, San Francisco, CA 94143 USA
[2] Botswana UPenn Partnership, Gaborone, Botswana
[3] Univ Penn, Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[4] Univ Botswana, Fac Hlth Sci, Gaborone, Botswana
[5] Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Houston, TX 77030 USA
[6] Baylor Coll Med, Natl Sch Trop Med, Houston, TX 77030 USA
来源
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2017年 / 29卷 / 08期
关键词
S; aureus; HIV; sub-Saharan Africa; nasal colonization; CARRIAGE; CHILDREN;
D O I
10.1080/09540121.2017.1282600
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
We sought to determine the clinical and epidemiologic determinants of Staphylococcus aureus nasal colonization in HIV-infected individuals at two outpatient centers in southern Botswana. Standard microbiologic techniques were used to identify S. aureus and methicillin-resistant S. aureus (MRSA). In a sample of 404 HIV-infected adults, prevalence of S. aureus nasal carriage was 36.9% (n=152) and was associated with domestic overcrowding and lower CD4 cell count. MRSA prevalence was low (n=13, 3.2%), but more common among individuals with asthma and eczema. The implications of these findings for HIV management are discussed.
引用
收藏
页码:961 / 965
页数:5
相关论文
共 24 条
[11]   Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004 [J].
Gorwitz, Rachel J. ;
Kruszon-Moran, Deanna ;
McAllister, Sigrid K. ;
McQuillan, Geraldine ;
McDougal, Linda K. ;
Fosheim, Gregory E. ;
Jensen, Bette J. ;
Killgore, George ;
Tenover, Fred C. ;
Kuehnert, Matthew J. .
JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (09) :1226-1234
[12]   Community-onset Staphylococcus aureus bacteraemia in hospitalised African children: high incidence in HIV-infected children and high prevalence of multidrug resistance [J].
Groome, M. J. ;
Albrich, W. C. ;
Wadula, J. ;
Khoosal, M. ;
Madhi, S. A. .
PAEDIATRICS AND INTERNATIONAL CHILD HEALTH, 2012, 32 (03) :140-146
[13]   Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk [J].
Herold, BC ;
Immergluck, LC ;
Maranan, MC ;
Lauderdale, DS ;
Gaskin, RE ;
Boyle-Vavra, S ;
Leitch, CD ;
Daum, RS .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (08) :593-598
[14]   Prevalence of methicillin-resistant Staphylococcus aureus nasal carriage among hospitalised patients with tuberculosis in rural KwaZulu-Natal [J].
Heysell, Scott K. ;
Shenoi, Sheela V. ;
Catterick, Kathryn ;
Thomas, Tania A. ;
Friedland, Gerald .
SAMJ SOUTH AFRICAN MEDICAL JOURNAL, 2011, 101 (05) :332-334
[15]  
Hidron Alicia I, 2010, Infect Drug Resist, V3, P73
[16]   Prevalence and behavioural risk factors of Staphylococcus aureus nasal colonization in community-based injection drug users [J].
Leung, N. S. ;
Padgett, P. ;
Robinson, D. A. ;
Brown, E. L. .
EPIDEMIOLOGY AND INFECTION, 2015, 143 (11) :2430-2439
[17]   Networks, resources and risk among women who use drugs [J].
Miller, M ;
Neaigus, A .
SOCIAL SCIENCE & MEDICINE, 2001, 52 (06) :967-978
[18]   Incidence and persistence of staphylococcus aureus nasal colonization in a community sample of HIV-infected and -uninfected drug users [J].
Miller, Maureen ;
Cespedes, Christian ;
Bhat, Meera ;
Vavagiakis, Peter ;
Klein, Robert S. ;
Lowy, Franklin D. .
CLINICAL INFECTIOUS DISEASES, 2007, 45 (03) :343-346
[19]   Unexpected absence of meticillin-resistant Staphylococcus aureus nasal carriage by healthcare workers in a tertiary hospital in Kenya [J].
Omuse, G. ;
Kariuki, S. ;
Revathi, G. .
JOURNAL OF HOSPITAL INFECTION, 2012, 80 (01) :71-73
[20]   Are Host Genetics the Predominant Determinant of Persistent Nasal Staphylococcus aureus Carriage in Humans? [J].
Ruimy, Raymond ;
Angebault, Cecile ;
Djossou, Felix ;
Dupont, Claire ;
Epelboin, Loic ;
Jarraud, Sophie ;
Armand Lefevre, Laurence ;
Bes, Michele ;
Lixandru, Brandusa Elena ;
Bertine, Melanie ;
El Miniai, Assiya ;
Renard, Magaly ;
Bettinger, Regis Marc ;
Lescat, Mathilde ;
Clermont, Olivier ;
Peroz, Gilles ;
Lina, Gerard ;
Tavakol, Mehri ;
Vandenesch, Francois ;
van Belkum, Alex ;
Rousset, Francois ;
Andremont, Antoine .
JOURNAL OF INFECTIOUS DISEASES, 2010, 202 (06) :924-934