An efficient procedure for the synthesis of benzimidazole derivatives using Yb(OTf)3 as catalyst under solvent-free conditions

被引：56
|
作者：
Wang, LM
Sheng, J
Tian, H
Qian, CT
机构：
[1] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China
[2] Chinese Acad Sci, Organomet Chem Lab, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 23期
关键词：
Yb(OTf)(3); benzimidazole; solvent-free reaction;
D O I：
10.1081/SCC-200039340
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
o-Diaminobenzene derivatives react smoothly with ortho-esters in the presence of 0.5 mol% of Yb(OTf)(3) under solvent-free conditions to afford the corresponding benzimidazole derivatives in good to excellent yields. In addition, Yb(OTf)(3) can be easily recovered almost quantitatively froth the aqueous layer after the reaction was completed, and it could be reused with no loss of activity.
引用
收藏
页码：4265 / 4272
页数：8
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