Chiral recognition of amino-acid esters by a glucose-derived macrocyclic receptor

被引：14
作者：
Dominique, Pit [1 ]
Schnurr, Martin [1 ]
Lewandowski, Bartosz [1 ]
机构：
[1] Swiss Fed Inst Technol, Lab Organ Chem, Vladimir Prelog Weg 1-5, CH-8093 Zurich, Switzerland
来源：
CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 28期
关键词：
49;
D O I：
10.1039/d1cc00878a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a glucose-based crown ether capable of chiral recognition of a wide range of amino-acid methyl esters in aqueous environments. The enantioselectivities towards amino-acids with extended hydrophobic side chains displayed by the glucose-derived macrocycle are among the highest observed for small molecule synthetic receptors to date.
引用
收藏
页码：3476 / 3479
页数：4
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