Atomic-level analysis of membrane-protein structure

被引：43

作者：

Hendrickson, Wayne A. ^{[1
,2
,3
]}

机构：

[1] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY USA

[2] Columbia Univ, Dept Physiol & Cellular Biophys, New York, NY USA

[3] NYSBC, New York, NY USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2016年 / 23卷 / 06期

关键词：

CRYOELECTRON MICROSCOPY; CUBIC PHASE; CHANNEL; CRYSTALLOGRAPHY;

D O I：

10.1038/nsmb.3215

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Membrane proteins are substantially more challenging than natively soluble proteins as subjects for structural analysis. Thus, membrane proteins are greatly underrepresented in structural databases. Recently, focused consortium efforts and advances in methodology for protein production, crystallographic analysis and cryo-EM analysis have accelerated the pace of atomic-level structure determination,of membrane proteins.

引用

页码：464 / 467

页数：4

共 50 条

[1] Atomic-level analysis of membrane-protein structure
Wayne A Hendrickson
Nature Structural & Molecular Biology, 2016, 23 : 464 - 467
[2] The first of its kindFirst atomic-level protein structure
Rebecca Kirk
Nature, 2014, 511 (Suppl 7509) : 13 - 13
[3] Direct observation of atomic-level fractal structure in a metallic glass membrane
Jiang, Hongyu
Xu, Jiyu
Zhang, Qinghua
Yu, Qian
Shen, Laiquan
Liu, Ming
Sun, Yitao
Cao, Chengrong
Su, Dong
Bai, Haiyang
Meng, Sheng
Sun, Baoan
Gu, Lin
Wang, Weihua
SCIENCE BULLETIN, 2021, 66 (13) : 1312 - 1318
[4] A Simple Atomic-Level Hydrophobicity Scale Reveals Protein Interfacial Structure
Kapcha, Lauren H.
Rossky, Peter J.
JOURNAL OF MOLECULAR BIOLOGY, 2014, 426 (02) : 484 - 498
[5] Atomic-level structural mapping of membrane protein interactions with drugs, antibodies, and ligands
Paes, Cheryl
JOURNAL OF BIOMOLECULAR SCREENING, 2008, 13 (07) : 712 - 713
[6] Atomic-level characterization of protein-protein association
Pan, Albert
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
[7] AN ATOMIC MODEL FOR THE STRUCTURE OF BACTERIORHODOPSIN, A 7-HELIX MEMBRANE-PROTEIN
CESKA, TA
HENDERSON, R
BALDWIN, JM
ZEMLIN, F
BECKMANN, E
DOWNING, K
ACTA PHYSIOLOGICA SCANDINAVICA, 1992, 146 : 31 - 40
[8] Atomic-level characterization of protein-protein association
Pan, Albert
Jacobson, Daniel
Yatsenko, Konstantin
Sritharan, Duluxan
Weinreich, Thomas
Shaw, David
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
[9] Atomic-level characterization of protein-protein association
Pan, Albert C.
Jacobson, Daniel
Yatsenko, Konstantin
Sritharan, Duluxan
Weinreich, Thomas M.
Shaw, David E.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (10) : 4244 - 4249
[10] Atomic-Level Characterization of Protein-Protein Association
Pan, Albert C.
Jacobson, Daniel
Borisov, Konstantin
Sritharan, Duluxan
Weinreich, Thomas M.
Shaw, David E.
BIOPHYSICAL JOURNAL, 2018, 114 (03) : 557A - 557A

← 1 2 3 4 5 →