Comparison of Drug Permeabilities and BCS Classification: Three Lipid-Component PAMPA System Method versus Caco-2 Monolayers

被引:48
作者
Teksin, Zeynep S. [1 ]
Seo, Paul R. [1 ]
Polli, James E. [1 ,2 ]
机构
[1] Univ Maryland, Sch Pharm, Baltimore, MD 21201 USA
[2] Gazi Univ, Dept Pharmaceut Technol, Fac Pharm, TR-06330 Ankara, Turkey
基金
美国国家卫生研究院;
关键词
biopharmaceutics classification system; Caco-2; membrane transport; PAMPA; permeability; IN-VITRO MODEL; ARTIFICIAL MEMBRANES; ABSORPTION; PREDICTION; TRANSPORT; ASSAY; PHARMACOKINETICS; BIOAVAILABILITY; CELLS; TOOL;
D O I
10.1208/s12248-010-9176-2
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:238 / 241
页数:4
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