Molecular characterization of Staphylococcus aureus in Lebanon

被引：46

作者：

Tokajian, S. T. ^{[1
]}

Abou Khalil, P.

Jabbour, D.

Rizk, M.

Farah, M. J.

Hashwa, F. A.

Araj, G. F. ^{[2
]}

机构：

[1] Lebanese Amer Univ, Dept Biol, Microbiol & Biotechnol Genom & Prote Res Ctr, Sch Arts & Sci, Byblos, Lebanon

[2] Amer Univ Beirut, Med Ctr, Dept Pathol & Lab Med, Beirut, Lebanon

来源：

EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 05期

关键词：

Bacterial infections; bacterial typing; methicillin-resistant S. aureus (MRSA); Staphylococcus aureus; staphyococcal infections; PANTON-VALENTINE LEUKOCIDIN; COMMUNITY; CHROMOSOME; STRAINS; MRSA; MEC; EPIDEMIOLOGY; PREVALENCE; INFECTIONS; ASSIGNMENT;

D O I：

10.1017/S0950268810000440

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Staphylococcus aureus is an important human pathogen and is a growing public health concern. In this study, 130 S. aureus, 93 methicillin-resistant S. aureus (M RSA) and 37 methicillin-sensitive S. aureus (MSSA), clinical isolates recovered from Lebanon were typed by protein A gene (spa) sequencing and multi-locus sequence typing (MLST). Forty-eight different spa types were identified and clustered into 30 different groups. MLST revealed 10 sequence types (STs) among the isolates. There were eight major MRSA clones defined as isolates with the same ST and the same SCCmec type. The majority of the PVL-positive isolates (53%) were ST80-MRSA-IVc. Systematic surveillance of both hospital and community isolates in Lebanon together with measures designed to limit the spread are required.

引用

页码：707 / 712

页数：6

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