Chemoenzymatic synthesis of 2-brorno-6-hydroxy-3-methoxy-2-cyclohexen-1-one

被引：0
|
作者：
Karaaslan, Emine Ozgul [1 ]
Toka, Yasemin [1 ]
机构：
[1] Kirikkale Univ, Fac Arts & Sci, Dept Chem, TR-71400 Kirikkale, Turkey
来源：
TURKISH JOURNAL OF CHEMISTRY | 2007年 / 31卷 / 02期
关键词：
chemoenzymatic synthesis; cyclic polyoxo cyclohexenones; manganese (III) acetate; acetoxylation;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-cyclohexen-1-one starting from cyclohexane-1,3-dione is reported. Manganese (III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of alpha'-acetoxy enone affords hydroxy-enone 5 and enone 4 with high enantiomeric excesses in good yields.
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页码：149 / 153
页数：5
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