Prevalence and Correlates of Suicidal Thoughts and Suicide Attempts in People Prescribed Pharmaceutical Opioids for Chronic Pain

被引:36
作者
Campbell, Gabrielle [1 ]
Bruno, Raimondo [3 ]
Darke, Shane [1 ]
Shand, Fiona [2 ]
Hall, Wayne [4 ,5 ]
Farrell, Michael [1 ]
Degenhardt, Louisa [1 ]
机构
[1] Univ New S Wales, Natl Drug & Alcohol Res Ctr, 22-32 King St, Randwick, NSW 2031, Australia
[2] Univ New S Wales, Black Dog Inst, Randwick, NSW 2031, Australia
[3] Univ Tasmania, Sch Med, Hobart, Tas, Australia
[4] Univ Queensland, Ctr Youth Subst Abuse Res, St Lucia, Qld, Australia
[5] Kings Coll London, Natl Addict Ctr, London WC2R 2LS, England
关键词
ideation-to-action; attempt; prescription opioids; chronic pain; suicide; cohort; 2007; NATIONAL-SURVEY; MENTAL-HEALTH; RISK-FACTORS; CHILDHOOD ABUSE; CLINICAL-TRIALS; IDEATION; COMORBIDITY; DEPRESSION; VERSION; GENDER;
D O I
10.1097/AJP.0000000000000283
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objectives: The main objectives of the paper were (1) to examine the prevalence of suicidality in a large community-based chronic pain sample taking prescribed opioids for chronic pain; and (2) to examine general and pain-specific factors that predict such ideation, and the transition from ideation to making a suicide attempt (ideation-to-action). Materials and Methods: Baseline data from the Pain and Opioids IN Treatment (POINT) study with a cohort of 1514 community-based people prescribed opioids for chronic noncancer pain across Australia. Results: Past 12-month suicidal ideation was reported by 36.5% of the cohort and 16.4% had made a lifetime suicide attempt (2.5% in the last 12 mo), after the onset of their pain condition. Suicidal ideation in the past 12 months was independently associated with a past suicide attempt [adjusted odds ratio (AOR)=4.82; 95% confidence interval, 2.43-9.56] and past 12-month depression (AOR=4.07, 95% confidence interval, 1.88-8.78). Only a lower pain self-efficacy score was independently associated with past 12-month ideation-to-action (AOR=0.98, 95%CI0.88-0.99). Notably, only general-suicide risk factors were associated with 12-month suicidal ideation; but for past year ideation-to-action, pain-specific factors also had independent associations. Discussion: The study is one of the first to comprehensively examine general and pain-specific risk factors for suicidality in a large chronic pain sample in which suicidal ideation was common. A low pain self-efficacy score was the only factor independently associated past 12-month ideation-to-action.
引用
收藏
页码:292 / 301
页数:10
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