Knowledge of antiretroviral regimen dosing and adherence: A longitudinal study

被引:85
作者
Miller, LG
Liu, HH
Hays, RD
Golin, CE
Ye, ZS
Beck, CK
Kaplan, AH
Wenger, NS
机构
[1] Harbor UCLA Med Ctr, Div Infect Dis, Torrance, CA 90502 USA
[2] Harbor UCLA Med Ctr, Div HIV Med, Torrance, CA 90502 USA
[3] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA
[4] Univ Calif Los Angeles, AIDS Inst Ctr AIDS Res, Los Angeles, CA USA
[5] Univ N Carolina, Dept Med, Chapel Hill, NC USA
[6] Univ N Carolina, Div Infect Dis, Chapel Hill, NC USA
关键词
D O I
10.1086/367857
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P = .03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.
引用
收藏
页码:514 / 518
页数:5
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