Chronic myeloid leukemia and BCR/ABL signal pathways are not associated with AKT1 pleckstrin homology domain (E17K) mutations

被引：3

作者：

He, Yanli ^{[1
]}

Zheng, Jine ^{[1
]}

Hu, Yanjie ^{[1
]}

Xiao, Hong ^{[1
]}

Liu, Jun ^{[1
]}

Li, Xiaoqing ^{[1
]}

Du, Wen ^{[1
]}

Chen, Xiangjun ^{[1
]}

Hu, Yu

Huang, Shiang ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Ctr Stem Cell Res & Applicat, Union Hosp, Inst Hematol,Tongji Med Coll, Wuhan 430022, Hubei, Peoples R China

来源：

EUROPEAN JOURNAL OF HAEMATOLOGY | 2010年 / 84卷 / 01期

关键词：

CHRONIC MYELOGENOUS LEUKEMIA; BILIARY-TRACT; CARCINOMAS; CANCER;

D O I：

10.1111/j.1600-0609.2009.01350.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：87 / 88

页数：2

共 13 条

[1] A transforming mutation in the pleckstrin homology domain of AKT1 in cancer [J].

Carpten, John D. ;

Faber, Andrew L. ;

Horn, Candice ;

Donoho, Gregory P. ;

Briggs, Stephen L. ;

Robbins, Christiane M. ;

Hostetter, Galen ;

Boguslawski, Sophie ;

Moses, Tracy Y. ;

Savage, Stephanie ;

Uhlik, Mark ;

Lin, Aimin ;

Du, Jian ;

Qian, Yue-Wei ;

Zeckner, Douglas J. ;

Tucker-Kellogg, Greg ;

Touchman, Jeffrey ;

Patel, Ketan ;

Mousses, Spyro ;

Bittner, Michael ;

Schevitz, Richard ;

Lai, Mei-Huei T. ;

Blanchard, Kerry L. ;

Thomas, James E. .

NATURE, 2007, 448 (7152) :439-U1

[2] MOLECULAR GENETIC ADVANCES IN CHRONIC MYELOGENOUS LEUKEMIA [J].

EPNER, DE ;

KOEFFLER, HP .

ANNALS OF INTERNAL MEDICINE, 1990, 113 (01) :3-6

[3] The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression [J].

Hui, Rosaline C. -Y. ;

Gomes, Ana R. ;

Constantinidou, Demetra ;

Costa, Joana R. ;

Karadedou, Christina T. ;

de Mattos, Silvia Fernandez ;

Wymann, Matthias P. ;

Brosens, Jan J. ;

Schulze, Almut ;

Lam, Eric W. -F. .

MOLECULAR AND CELLULAR BIOLOGY, 2008, 28 (19) :5886-5898

[4] Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias [J].

Kim, M. S. ;

Jeong, E. G. ;

Yoo, N. J. ;

Lee, S. H. .

BRITISH JOURNAL OF CANCER, 2008, 98 (09) :1533-1535

[5] Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung [J].

Malanga, Donatella ;

Scrima, Marianna ;

De Marco, Carmela ;

Fabiani, Fernanda ;

De Rosa, Nicla ;

De Gisi, Silvia ;

Malara, Natalia ;

Savino, Rocco ;

Rocco, Gaetano ;

Chiappetta, Gennaro ;

Franco, Renato ;

Tirino, Virginia ;

Pirozzi, Giuseppe ;

Viglietto, Giuseppe .

CELL CYCLE, 2008, 7 (05) :665-669

[6] AKT/PKB signaling: Navigating downstream [J].

Manning, Brendan D. ;

Cantley, Lewis C. .

CELL, 2007, 129 (07) :1261-1274

[7] Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia [J].

Ren, R .

NATURE REVIEWS CANCER, 2005, 5 (03) :172-183

[8] Analysis of oncogenic AKT1 p.E17K mutation in carcinomas of the biliary tract and liver [J].

Riener, M-O ;

Bawohl, M. ;

Clavien, P-A ;

Jochum, W. .

BRITISH JOURNAL OF CANCER, 2008, 99 (05) :836-836

[9] Rare PIK3CA hotspot mutations in carcinomas of the biliary tract [J].

Riener, Marc-Oliver ;

Bawohl, Marion ;

Clavien, Pierre-Alain ;

Jochum, Wolfram .

GENES CHROMOSOMES & CANCER, 2008, 47 (05) :363-367

[10] Janus kinase 2: A critical target in chronic myelogenous leukemia [J].

Samanta, Ajoy K. ;

Lin, Hui ;

Sun, Tong ;

Kantarjian, Hagop ;

Arlinghaus, Ralph B. .

CANCER RESEARCH, 2006, 66 (13) :6468-6472

← 1 2 →