SAFETY AND EFFICACY OF EVINACUMAB, A MONOCLONAL ANTIBODY TO ANGPTL3, IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: A SINGLE-ARM, OPEN-LABEL, PROOF-OF-CONCEPT STUDY

被引：7

作者：

Gaudet, Daniel ^{[1
,2
]}

Gipe, Daniel ^{[3
]}

Hovingh, Kees ^{[4
]}

Ahmad, Zahid ^{[5
]}

Cuchel, Marina ^{[6
]}

Shah, Prediman ^{[7
]}

Chyu, Kuang-Yuh ^{[7
]}

Pordy, Robert ^{[3
]}

Sasiela, William ^{[3
]}

Chan, Kuo-Chen ^{[3
]}

Khoury, Etienne ^{[1
,2
]}

机构：

[1] Univ Montreal, Dept Med, ECOGENE Clin Res Ctr 21, Chicoutimi, PQ, Canada

[2] Lipid Clin, Chicoutimi, PQ, Canada

[3] Regeneron Pharmaceut Inc, 777 Old Saw Mill River Rd, Tarrytown, NY 10591 USA

[4] Acad Med Ctr, Dept Vasc Med, Amsterdam, Netherlands

[5] Univ Texas Southwestern Med Ctr Dallas, Div Endocrinol, Dallas, TX 75390 USA

[6] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

[7] Cedars Sinai Med Ctr, Cedars Sinai Heart Inst, Los Angeles, CA 90048 USA

来源：

关键词：

D O I：

10.1016/j.atherosclerosis.2017.06.057

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

LB1:1

引用

页码：E9 / E9

页数：1