Realistic modeling of transcranial current stimulation: The electric field in the brain

被引：28

作者：

Miranda, Pedro C. ^{[1
]}

Callejon-Leblic, Maria A. ^{[2
]}

Salvador, Ricardo ^{[3
]}

Ruffini, Giulio ^{[3
]}

机构：

[1] Univ Lisbon, Fac Ciencias, Inst Biofis & Engn Biomed, P-1749016 Lisbon, Portugal

[2] Univ Seville, Escuela Tecn Super Ingn, Grp Ingn Biomed, Seville 41092, Spain

[3] Neuroelect Barcelona, Barcelona 08035, Spain

来源：

CURRENT OPINION IN BIOMEDICAL ENGINEERING | 2018年 / 8卷

关键词：

Computational models; Dose; Electric field; Multi-electrode; Optimization; Transcranial current stimulation;

D O I：

10.1016/j.cobme.2018.09.002

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Computational models of transcranial current stimulation (tCS) derived from MRI predict the electric field distribution in individual brains with reasonable accuracy and should be used to guide the selection of optimal stimulation parameters. Some recent advances that support this claim are: free toolboxes to generate individual head models for electric field calculations, the validation of model predictions in comparison to in-vivo measurements, and new algorithms to optimize the electric field at the target with multi-electrode stimulation. Electrical impedance tomography may provide subject-specific estimates of the electric conductivity of the scalp and skull, thereby improving the accuracy of the electric field calculations. In the future, electric field models should be coupled with electro-physiological models to predict experimental outcomes.

引用

页码：20 / 27

页数：8

共 55 条

[1] Electrical Impedance Tomography: Tissue Properties to Image Measures [J].

Adler, Andy ;

Boyle, Alistair .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2017, 64 (11) :2494-2504

[2] Are current flow models for transcranial electrical stimulation fit for purpose? [J].

Bestmann, Sven ;

Ward, Nick .

BRAIN STIMULATION, 2017, 10 (04) :865-866

[3] Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro [J].

Bikson, M ;

Inoue, M ;

Akiyama, H ;

Deans, JK ;

Fox, JE ;

Miyakawa, H ;

Jefferys, JGR .

JOURNAL OF PHYSIOLOGY-LONDON, 2004, 557 (01) :175-190

[4] Rigor and reproducibility in research with transcranial electrical stimulation: An NIMH-sponsored workshop [J].

Bikson, Marom ;

Brunoni, Andre R. ;

Charvet, Leigh E. ;

Clark, Vincent P. ;

Cohen, Leonardo G. ;

Deng, Zhi-De ;

Dmochowski, Jacek ;

Edwards, Dylan J. ;

Frohlich, Flavio ;

Kappenman, Emily S. ;

Lim, Kelvin O. ;

Loo, Colleen ;

Mantovani, Antonio ;

McMullen, David P. ;

Parra, Lucas C. ;

Pearson, Michele ;

Richardson, Jessica D. ;

Rumsey, Judith M. ;

Sehatpour, Pejman ;

Sommers, David ;

Unal, Gozde ;

Wassermann, Eric M. ;

Woods, Adam J. ;

Lisanby, Sarah H. .

BRAIN STIMULATION, 2018, 11 (03) :465-480

[5] Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016 [J].

Bikson, Marom ;

Grossman, Pnina ;

Thomas, Chris ;

Zannou, Adantchede Louis ;

Jiang, Jimmy ;

Adnan, Tatheer ;

Mourdoukoutas, Antonios P. ;

Kronberg, Greg ;

Truong, Dennis ;

Boggio, Paulo ;

Brunoni, Andre R. ;

Charvet, Leigh ;

Fregni, Felipe ;

Fritsch, Brita ;

Gillick, Bernadette ;

Hamilton, Roy H. ;

Hampstead, Benjamin M. ;

Jankord, Ryan ;

Kirton, Adam ;

Knotkova, Helena ;

Liebetanz, David ;

Liu, Anli ;

Loo, Colleen ;

Nitsche, Michael A. ;

Reis, Janine ;

Richardson, Jessica D. ;

Rotenberg, Alexander ;

Turkeltaub, Peter E. ;

Woods, Adam J. .

BRAIN STIMULATION, 2016, 9 (05) :641-661

[6] The electric field in the cortex during transcranial current stimulation [J].

Cavaleiro Miranda, Pedro ;

Mekonnen, Abeye ;

Salvador, Ricardo ;

Ruffmi, Giulio .

NEUROIMAGE, 2013, 70 :48-58

[7] Neuromodulation of Axon Terminals [J].

Chakraborty, Darpan ;

Truong, Dennis Q. ;

Bikson, Marom ;

Kaphzan, Hanoch .

CEREBRAL CORTEX, 2018, 28 (08) :2786-2794

[8] Low-Frequency Conductivity Tensor Imaging of the Human Head In Vivo Using DT-MREIT: First Study [J].

Chauhan, Munish ;

Indahlastari, Aprinda ;

Kasinadhuni, Aditya K. ;

Schar, Michael ;

Mareci, Thomas H. ;

Sadleir, Rosalind J. .

IEEE TRANSACTIONS ON MEDICAL IMAGING, 2018, 37 (04) :966-976

[9]

Corazza MF, 2018, IEEE T BIO-MED ENG, P1

[10] Effects of transcranial direct current stimulation for treating depression: A modeling study [J].

Csifcsak, Gabor ;

Boayue, Nya Mehnwolo ;

Puonti, Oula ;

Thielscher, Axel ;

Mittner, Matthias .

JOURNAL OF AFFECTIVE DISORDERS, 2018, 234 :164-173

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