HOTAIR lifts noncoding RNAs to new levels

被引：129
作者：
Woo, Caroline J.
Kingston, Robert E. [1 ]
机构：
[1] Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA
来源：
CELL | 2007年 / 129卷 / 07期
关键词：
D O I：
10.1016/j.cell.2007.06.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
It is not clear to what extent noncoding RNAs regulate the homeobox (HOX) genes that encode key regulators of development in the embryo. In this issue, Rinn et al. (2007) characterize noncoding RNAs that regulate HOX genes and discover one, HOTAIR, that unexpectedly regulates a HOX gene cluster on a different chromosome than the HOX cluster that encodes it.
引用
收藏
页码：1257 / 1259
页数：4
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