Sensing behavior of fluorescent cyclodextrin/peptide hybrids bearing a macrocyclic metal complex

被引：16
作者：
Furukawa, S [1 ]
Mihara, H [1 ]
Ueno, A [1 ]
机构：
[1] Tokyo Inst Technol, Dept Bioengn, Grad Sch Biosci & Biotechnol, Yokohama, Kanagawa 2268501, Japan
来源：
MACROMOLECULAR RAPID COMMUNICATIONS | 2003年 / 24卷 / 02期
关键词：
cyclodextrins; fluorescence; host-guest systems; macrocyclic polyamine; peptides;
D O I：
10.1002/marc.200390033
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Two kinds of cyclodextrin/peptide (CD/peptide) hybrids bearing Zn-II-cyclen or cyclen, dansyl and beta-cyclodextrin (beta-CD) units have been synthesized as chemosensors for organic anionic molecules, Zn-II-cyclen serves as a ligand site and beta-CD is a receptor site for guest molecules, wile the dansyl unit acts as a fluorescent probe. Examination of the fluorescence behaviors of these CD/peptides suggested that the hybrid containing Zn2+ has larger binding constants with respect to anionic molecules than that without Zn2+.
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收藏
页码：202 / 206
页数：5
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