Limbic Encephalitis Associated with Human Herpesvirus-7 (HHV-7) in an Immunocompetent Adult: The First Reported Case in Japan

被引：8

作者：

Aburakawa, Yoko ^{[1
,2
]}

Katayama, Takayuki ^{[1
]}

Saito, Tsukasa ^{[1
]}

Sawada, Jun ^{[1
]}

Suzutani, Tatsuo ^{[3
]}

Aizawa, Hitoshi ^{[1
,4
]}

Hasebe, Naoyuki ^{[1
]}

机构：

[1] Asahikawa Med Univ, Dept Med 1, Div Neurol, Asahikawa, Hokkaido, Japan

[2] Natl Hosp Org, Asahikawa Med Ctr, Dept Neurol, Asahikawa, Hokkaido, Japan

[3] Fukushima Med Univ, Dept Microbiol, Fukushima, Hokkaido, Japan

[4] Tokyo Med Univ, Dept Neurol, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2017年 / 56卷 / 14期

关键词：

encephalitis; human herpesvirus-7; adult; immunocompetent; CELL TRANSPLANT RECIPIENT; POLYMERASE-CHAIN-REACTION; CEREBROSPINAL-FLUID; PERIPHERAL-BLOOD; AND-7; INFECTIONS; ACUTE MYELITIS; HUMAN-HERPESVIRUS-7; DNA;

D O I：

10.2169/internalmedicine.56.8185

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 35-year-old male who had not previously suffered any major illnesses was admitted to our hospital because of general fatigue, fever, headache, vomiting, consciousness disturbance, and seizures. A neurological examination showed that he was in a semi-comatose state and exhibited neck stiffness. Brain magnetic resonance imaging detected high-intensity areas in the bilateral hippocampi and periventricular white matter. A cerebrospinal fluid examination revealed mononuclear pleocytosis, an elevated protein level, and positivity for human herpesvirus-7 (HHV-7) DNA. The patient's condition improved after the administration of methylprednisolone, intravenous immunoglobulins, and acyclovir. This is the first known case of limbic encephalitis associated with HHV-7 in an immunocompetent Japanese adult.

引用

页码：1919 / 1923

页数：5

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