Chromatin remodeling machines: similar motors, ulterior motives

被引：148
作者：
Cairns, BR [1 ]
机构：
[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 01期
关键词：
D O I：
10.1016/S0968-0004(97)01160-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chromatin is a dynamic material; chromatin structures can repress transcription and their remodeling accompanies activation. Recent biochemical studies in Drosophila have revealed three multi-protein complexes with ATP-dependent chromatin restructuring activities. Although all contain the ATPase ISWI, their properties in vitro are markedly different, distinct from SWI-SNF and reveal intriguing connections to both transcription and chromatin assembly.
引用
收藏
页码：20 / 25
页数：6
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