Decrease in red cell distribution width as a useful predictor of success after catheter ablation for atrial fibrillation: a retrospective multi-center study

被引：1

作者：

Yoshimoto, Issei ^{[1
,2
]}

Inoue, Koichi ^{[1
,4
]}

Oketani, Naoya ^{[2
,3
]}

Ichiki, Hitoshi ^{[2
]}

Okada, Masato ^{[1
]}

Tanaka, Nobuaki ^{[1
]}

Hirao, Yuko ^{[1
]}

Oka, Takafumi ^{[1
]}

Tanaka, Koji ^{[1
]}

Harada, Shinichi ^{[1
]}

Onishi, Toshinari ^{[1
]}

Koyama, Yasushi ^{[1
]}

Okamura, Atsunori ^{[1
]}

Iwakura, Katsuomi ^{[1
]}

Fujii, Kenshi ^{[1
]}

Miyata, Masaaki ^{[2
,3
]}

Ohishi, Mitsuru ^{[2
]}

机构：

[1] Sakurabashi Watanabe Hosp, Cardiovasc Ctr, Kita Ku, 2-4-32 Umeda, Osaka 5300001, Japan

[2] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Cardiovasc Med & Hypertens, Kagoshima, Japan

[3] Kagosima City Hosp, Kagoshima, Japan

[4] Natl Hosp Org, Osaka Natl Hosp, Chuo Ward, 2 Chome 1-14 Hoenzaka, Osaka 5400006, Japan

来源：

HEART AND VESSELS | 2022年 / 37卷 / 01期

基金：

日本学术振兴会;

关键词：

Atrial fibrillation; Catheter ablation; Recurrence; Red cell distribution width; HEART-FAILURE; PROGNOSTIC MARKER; INFLAMMATION; RECURRENCE; MORTALITY; ANEMIA;

D O I：

10.1007/s00380-021-01891-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Red cell distribution width (RDW) is reportedly associated with cardiovascular events, including atrial fibrillation (AF). We investigated whether the RDW values were associated with the outcomes of catheter ablation for AF. This retrospective multicenter study included 501 patients with AF (239 paroxysmal AF cases, 196 persistent AF cases, and 66 long-standing persistent AF cases) who underwent initial AF ablation between March 2017 and May 2018. The RDW values were evaluated before and at 1-3 months after the procedure. The patients were stratified based on the recurrence of AF within 1 year after the index procedure with a blanking period of 3 months into recurrence group (107 patients, 21.4%) and no-recurrence group (394 patients, 78.6%). There were no significant differences in preoperative RDW values between the groups (p = 0.37). The RDW value did not change significantly after the ablation in the recurrence group (13.55-13.60%, p = 0.37), although it decreased significantly in the no-recurrence group (13.64-13.37%, p < 0.001). Multivariate Cox proportional hazards regression analyses revealed that a postoperative change in RDW (Delta RDW) was independently associated with AF recurrence (hazard ratio 2.00, 95% confidence interval 1.42-2.76, p < 0.001). Receiver operating characteristic curve analysis revealed that a Delta RDW cut-off value of - 0.1% provided a c-statistic of 0.65 for predicting AF recurrence. Decrease in RDW during the blanking period after ablation independently predicted the 1-year success of AF ablation.

引用

页码：99 / 109

页数：11

共 34 条

[11] Role of inflammation in initiation and perpetuation of atrial fibrillation - A systematic review of the published data [J].