Gallium trichloride-catalyzed exhaustive α-ethynylation reaction of 1-silylacetylenes

被引：10

作者：

Amemiya, Ryo ^{[1
]}

Yamaguchi, Masahiko ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Organ Chem, Sendai, Miyagi 9808578, Japan

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 07期

关键词：

deprotonation; 1,4-enynes; ethynylation; gallium trichloride; propargylgallium; 1-silylacetylenes;

D O I：

10.1002/adsc.200600399

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Gallium trichloride (GaCl3) catalyzes the ethynylation reaction of a 1,4-enyne with chlorosilyl-acetylene at the propargyl position giving a triethynylvinylmethane. This catalytic method can be applied to the exhaustive alpha-ethynylation of 1-silylacetylenes possessing less acidic propargyl protons, and mono-, di-, and triethynylated products are obtained depending on the structure of the starting materials.

引用

页码：1011 / 1014

页数：4

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