Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens

被引：61

作者：

Trotta, MP ^{[1
]}

Ammassari, A

Cozzi-Lepri, A

Zaccarelli, M

Castelli, F

Narciso, P

Melzi, S

De Luca, A

Monforte, AD

Antinori, A

机构：

[1] L Spallanzani IRCCS, Ist Nazl Malattie Infett, Rome, Italy

[2] Univ Cattolica Sacro Cuore, Ist Clin Malattie Infett, Rome, Italy

[3] UCL Royal Free & Univ Coll Med Sch, London, England

[4] Univ Brescia, Ist Malattie Infett & Trop, Brescia, Italy

[5] Univ Milan, Ist Malattie Infett & Trop, Milan, Italy

来源：

AIDS | 2003年 / 17卷 / 07期

关键词：

D O I：

10.1097/00002030-200305020-00026

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The difference between adherence to non-nucleoside reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI)-based regimens was investigated. Better adherence was found in NNRTI-treated patients, especially when efavirenz was included in the regimen, compared with single PI-treated patients and in those with CD4 cell counts less than 200x1066/l. By contrast, younger age, self-report of active drug use, fatigue or vomiting negatively affected adherence. Self-reported sexual dysfunction was significantly associated with non-adherence only in PI-treated individuals.

引用

页码：1099 / 1102

页数：4

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