Bacterial interplay at intestinal mucosal surfaces: implications for vaccine development

被引：10

作者：

Autenrieth, IB ^{[1
]}

Schmidt, MA

机构：

[1] Univ Tubingen, Inst Med Mikrobiol, D-72076 Tubingen, Germany

[2] Univ Munster, Zentrum Mol Biol Entzundung, Inst Infektiol, D-48149 Munster, Germany

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 10期

关键词：

D O I：

10.1016/S0966-842X(00)01828-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of molecular syringes' in several important gastrointestinal pathogens including Escherichia coli, Salmonella, Shigella and Yersinia, together with a better understanding of M cells and the mucosal immune system, has advanced our appreciation of multistage microorganism-host cell interactions. Recent studies suggest that these molecular strategies could be adapted for the development of modular mucosal vaccines.

引用

页码：457 / 464

页数：8

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