The activities of the E3 ubiquitin ligase COP1/SPA, a key repressor in light signaling

被引：192

作者：

Hoecker, Ute ^{[1
]}

机构：

[1] Univ Cologne, Bot Inst & Cluster Excellence Plant Sci CEPLAS, Bioctr, Zulpicher Str 47b, D-50674 Cologne, Germany

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2017年 / 37卷

关键词：

SPA PROTEINS; BLUE-LIGHT; DEPENDENT INTERACTION; ARABIDOPSIS COP1; CONSTITUTIVE PHOTOMORPHOGENIC1; GENE-EXPRESSION; FLOWERING TIME; CRYPTOCHROME; REPEAT DOMAIN; RED-LIGHT;

D O I：

10.1016/j.pbi.2017.03.015

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Light is a critical signal to integrate plant growth and development with the environment. Downstream of photoreceptors, the E3 ubiquitin ligase COP1/SPA is a key repressor of photomorphogenesis which targets many positive regulators of light signaling, mainly transcription factors, for degradation in darkness. In light-grown plants COP1/SPA activity is repressed, allowing light responses to occur. This review provides an overview on our current knowledge on COP1/SPA repressor function, focusing in particular on the roles of the respective protein domains and the mechanisms of light-induced inactivation of COP1/SPA. Moreover, we summarize how COP1 activity is regulated by other interacting proteins, such as a SUMO E3 ligase and Phytochrome-Interacting Factors (PIFs), as well as by hormones. At last, several novel functions of COP1 that were recently revealed are included.

引用

页码：63 / 69

页数：7

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