Use of Natural Components Derived from Oil Seed Plants for Treatment of Inflammatory Skin Diseases

被引:3
|
作者
Styrczewska, Monika [1 ]
Zuk, Magdalena [1 ]
Boba, Aleksandra [1 ]
Zalewski, Iwan [1 ]
Kulma, Anna [1 ]
机构
[1] Wroclaw Univ, Dept Genet Biochem, Fac Biotechnol, Przybyszewskiego St 63, PL-51148 Wroclaw, Poland
关键词
Inflammatory skin diseases; oil; terpenoids; carotenoids; fatty acid; phenylpropanoids; NF-KAPPA-B; EXHIBITS ANTIINFLAMMATORY ACTIVITY; METABOLISM-PROMOTING ACTIVITIES; MACROCYCLIC DITERPENE CASBENE; ALLERGIC CONTACT-DERMATITIS; INDUCED OXIDATIVE STRESS; FATTY-ACID-COMPOSITION; COMMUNIS L SEEDLINGS; VIRGIN OLIVE OIL; VITAMIN-E;
D O I
10.2174/1381612825666190716111700
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals, assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids, tocopherol and polyphenols.
引用
收藏
页码:2241 / 2263
页数:23
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