The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals, assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids, tocopherol and polyphenols.
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Chinese Acad Forestry, Res Inst Subtrop Forestry, State Forestry Adm, Hangzhou 311400, Zhejiang, Peoples R ChinaChinese Acad Forestry, Res Inst Subtrop Forestry, State Forestry Adm, Hangzhou 311400, Zhejiang, Peoples R China
Luo, Fan
Fei, Xueqian
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Chinese Acad Forestry, Res Inst Subtrop Forestry, State Forestry Adm, Hangzhou 311400, Zhejiang, Peoples R ChinaChinese Acad Forestry, Res Inst Subtrop Forestry, State Forestry Adm, Hangzhou 311400, Zhejiang, Peoples R China
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Vancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, CanadaVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Sharma, Manju
Levenson, Corey
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Santalis Pharmaceut Inc, San Antonio, TX USAVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Levenson, Corey
Browning, John C.
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Texas Dermatol & Laser Specialists, San Antonio, TX USAVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Browning, John C.
Becker, Emily M.
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Texas Dermatol & Laser Specialists, San Antonio, TX USAVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Becker, Emily M.
Clements, Ian
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Santalis Pharmaceut Inc, San Antonio, TX USAVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Clements, Ian
Castella, Paul
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Santalis Pharmaceut Inc, San Antonio, TX USAVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Castella, Paul
Cox, Michael E.
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Vancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada
Univ British Columbia, Dept Urol Sci, Vancouver, BC, CanadaVancouver Coastal Hlth Res Inst, Vancouver Prostate Ctr, Vancouver, BC, Canada