共 50 条
Neurobehavioral development of common marmoset monkeys
被引:50
|作者:
Schultz-Darken, Nancy
[1
]
Braun, Katarina M.
[1
,2
]
Emborg, Marina E.
[1
,2
,3
]
机构:
[1] Univ Wisconsin, Wisconsin Natl Primate Res Ctr, Madison, WI USA
[2] Univ Wisconsin, Med Scientist Training Program, Madison, WI USA
[3] Univ Wisconsin, Dept Med Phys, 1530 Med Sci Ctr, Madison, WI 53706 USA
关键词:
behavior;
developmental stages;
common marmoset;
neurodevelopment;
assessment scales;
CALLITHRIX-JACCHUS-JACCHUS;
PRIMARY VISUAL-CORTEX;
HEAD-COCKING;
POSTNATAL-DEVELOPMENT;
MULTIPLE-SCLEROSIS;
NEUROSCIENCE RESEARCH;
SAGUINUS-FUSCICOLLIS;
BIOMEDICAL-RESEARCH;
PARKINSONS-DISEASE;
NONHUMAN-PRIMATES;
D O I:
10.1002/dev.21360
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Common marmoset (Callithrix jacchus) monkeys are a resource for biomedical research and their use is predicted to increase due to the suitability of this species for transgenic approaches. Identification of abnormal neurodevelopment due to genetic modification relies upon the comparison with validated patterns of normal behavior defined by unbiased methods. As scientists unfamiliar with nonhuman primate development are interested to apply genomic editing techniques in marmosets, it would be beneficial to the field that the investigators use validated methods of postnatal evaluation that are age and species appropriate. This review aims to analyze current available data on marmoset physical and behavioral postnatal development, describe the methods used and discuss next steps to better understand and evaluate marmoset normal and abnormal postnatal neurodevelopment. (c) 2015 Wiley Periodicals, Inc. Dev Psychobiol 58: 141-158, 2016.
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页码:141 / 158
页数:18
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