Lipids control mucus production in cystic fibrosis

被引：6
|
作者：
Gulbins, Erich [1 ]
机构：
[1] Univ Duisburg Essen, Dept Mol Biol, Essen, Germany
来源：
NATURE MEDICINE | 2010年 / 16卷 / 03期
关键词：
ACTIVATED-RECEPTOR-GAMMA; ACCUMULATION; CELLS;
D O I：
10.1038/nm0310-267
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Altered lipid metabolism underlies the production of excess mucus in a mouse model of cystic fibrosis (313-318). The findings point to the nuclear receptor peroxisome proliferator-activated receptor-gamma (PPAR-gamma) as a potential therapeutic target in this disease.
引用
收藏
页码：267 / 268
页数：3
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