Periodontal Wound Healing and Tissue Regeneration: A Narrative Review

被引：94
作者：
Cho, Young-Dan [1 ,2 ,3 ]
Kim, Kyoung-Hwa [1 ,2 ,3 ]
Lee, Yong-Moo [1 ,2 ]
Ku, Young [1 ,2 ]
Seol, Yang-Jo [1 ,2 ,3 ]
机构：
[1] Seoul Natl Univ, Sch Dent, Dept Periodontol, Seoul 03080, South Korea
[2] Seoul Natl Univ, Dent Res Inst, Seoul 03080, South Korea
[3] Seoul Natl Univ, Dent Hosp, Seoul 03080, South Korea
来源：
PHARMACEUTICALS | 2021年 / 14卷 / 05期
基金：
新加坡国家研究基金会;
关键词：
periodontium; periodontal tissue regeneration; wound healing; PLATELET-RICH PLASMA; COLLAGEN MEMBRANES; INTRABONY DEFECTS; IMPLANT PLACEMENT; SOFT-TISSUE; DIODE-LASER; THERAPY; BONE; SKIN; PHOTOBIOMODULATION;
D O I：
10.3390/ph14050456
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, including a resection of the gingiva or the alveolar bone. The periodontal wound healing process is slightly different from cutaneous wound healing and is similar to fetal healing, being almost scar-free. The aim of this review article is to provide an overview of periodontal wound healing and discuss various surgical and pharmaceutical approaches to achieve stable wound healing and improve the treatment outcomes. In addition, detrimental and limiting factors that induce a compromised prognosis are discussed, along with the perspective and future direction for successful periodontal tissue regeneration.
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页数：17
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