Clinical use of plasma chitotriosidase in severe sepsis

被引：4

作者：

Chiarla, Carlo ^{[1
]}

Giovannini, Ivo ^{[1
]}

Antuzzi, Daniela ^{[2
]}

Piras, Andrea ^{[2
]}

Ardito, Francesco ^{[3
]}

Giuliante, Felice ^{[3
]}

机构：

[1] Univ Cattolica Sacro Cuore, CNR, IASI Ctr Pathophysiol Shock, Agostino Gemelli Hosp, I-00168 Rome, Italy

[2] Univ Cattolica Sacro Cuore, Agostino Gemelli Hosp, Inst Pediat, I-00168 Rome, Italy

[3] Univ Cattolica Sacro Cuore, Agostino Gemelli Hosp, Dept Surg Sci, Hepatobiliary Surg Unit, I-00168 Rome, Italy

来源：

CURRENT MEDICAL RESEARCH AND OPINION | 2016年 / 32卷 / 02期

关键词：

Critical illness; Hypocholesterolemia; Intensive care; Monitoring; Plasma chitotriosidase; Sepsis; FUNGAL; MARKER;

D O I：

10.1185/03007995.2015.1118370

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.

引用

页码：273 / 276

页数：4

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