Endoscopic band ligation without resection in selected patients for small and superficial upper gastrointestinal tract lesions

被引:0
作者
Ibanez-Sanz, Gemma [1 ]
Gornals, Joan B. [1 ]
Rivas, Laura [1 ]
Salord, Silvia [1 ]
Paules, Maria J. [2 ]
Botargues, Josep M. [1 ]
Galan, Maica [3 ]
机构
[1] Hosp Univ Bellvitge IDIBELL, Dept Digest Dis, Endoscopy Unit, Feixa Llarga S-N, Lhospitalet De Llobregat 08907, Barcelona, Spain
[2] Hosp Univ Bellvitge IDIBELL, Dept Pathol Anat, Feixa Llarga S-N, Lhospitalet De Llobregat 08907, Barcelona, Spain
[3] Inst Catala Oncol DiR IDIBELL, Dept Med Oncol, Lhospitalet De Llobregat, Barcelona, Spain
关键词
Endoscopic band ligation; Autoamputation; Early lesions; Superficial lesions; Small upper GI-lesions; Endoscopic mucosal resection; Duette mucosectomy; LYMPH-NODE METASTASIS; RISK; CARCINOIDS; CANCER; TUMORS;
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and aim: The aim of this study was to evaluate the efficacy of endoscopic band ligation (EBL) in carefully selected patients who would benefit from this method of resection. Methods: Patients with early upper gastrointestinal and small (< 15 mm) lesions treated with EBL (Duette Multi-Band Mucosectomy) were prospectively recruited and retrospectively analyzed between 2010 and 2015. All cases were discussed in a multidisciplinary cancer committee and it was concluded that, owing to patient conditions, surgery was not possible and that not conducting histology would not change the clinical management. A first endoscopic control with biopsies was planned at 4-8 weeks. If there was no persistence of the lesion, new controls were programmed at 6 and 12 months. Results: The group (n = 12) included 5 esophagus lesions (adenosquamous carcinoma, n = 1; carcinoma squamous, n = 2; adenocarcinoma, n = 2); 4 gastric lesions (high grade dysplasia, n = 1; adenocarcinoma, n = 2; neuroendocrine tumor [NET], n = 1), and 3 duodenal lesions (NETs) (n = 3). The mean tumor diameter was 9.6 +/- 2.8 mm (range 4-15). Only one minor adverse event was described. At first follow-up (4-8 weeks), there was 91.6% and 75% of endoscopic and histological remission, respectively. At 6-month follow-up there was 70% of both endoscopic remission and negative biopsies. And at 12 months, there was 100% and 75% of endoscopic and histological remission, respectively. Persisting lesions were T1 cancers. The median follow-up was 30.6 months. Conclusion: EBL without resection is an easy and safe technique that should be considered in patients with multiple morbidities and small superficial UGI lesions.
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页码:250 / 256
页数:7
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