ACID-BASE PROPERTIES OF PENICILLINS AND CEPHALOSPORINS (A REVIEW)

被引：24
|
作者：
Alekseev, V. G. [1 ]
机构：
[1] Tver State Univ, Tver 170013, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 01期
关键词：
acidity of penicillins; acidity of cephalosporins; CAPILLARY-ZONE-ELECTROPHORESIS; BETA-LACTAM ANTIBIOTICS; DISSOCIATION-CONSTANTS; AQUEOUS-SOLUTION; PHYSICOCHEMICAL PROPERTIES; IONIZATION-CONSTANTS; TERNARY COMPLEXES; PH-POTENTIOMETRY; DEGRADATION; STABILITY;
D O I：
10.1007/s11094-010-0389-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Published data on the acid-base properties of penicillin and cephalosporin antibiotics are summarized and systematized. It is suggested to classify penicillins and cephalosporins with respect to the acid-base type. The influence of the structure of antibiotics and the conditions and method used for determining the ionization constants of proton-donor groups in antibiotics are considered.
引用
收藏
页码：14 / 24
页数：11
相关论文
共 50 条
  • [21] Structure and Acid-Base Properties of 1-Propylimidazole-4,5-dicarboxylic Acid
    Brusina, M. A.
    Lysova, S. S.
    Oskorbin, A. A.
    Ramsh, S. M.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2023, 93 (05) : 1069 - 1079
  • [22] Acid-base and metal ion-binding properties of thiopyrimidine derivatives
    Sigel, Astrid
    Operschall, Bert P.
    Matera-Witkiewicz, Agnieszka
    Swiatek-Kozlowska, Jolanta
    Sigel, Helmut
    COORDINATION CHEMISTRY REVIEWS, 2016, 327 : 200 - 220
  • [23] Structure and Acid-Base Properties of 1-Propylimidazole-4,5-dicarboxylic Acid
    M. A. Brusina
    S. S. Lysova
    A. A. Oskorbin
    S. M. Ramsh
    Russian Journal of General Chemistry, 2023, 93 : 1069 - 1079
  • [24] Exploring the acid-base surface properties of vivianite crystals in aqueous solution
    Hong, Tianqiu
    Wei, Lin
    Li, Ziyue
    Wang, Yuanhui
    Zhang, Qiang
    Luo, Lei
    Zhang, Tingting
    Li, Ruolan
    Tang, Yiming
    SURFACE AND INTERFACE ANALYSIS, 2023, 55 (12) : 871 - 879
  • [25] ACID-BASE PROPERTIES OF THYMOPOIETIN-TYPE TRIPEPTIDES AND TETRAPEPTIDES AND THEIR DERIVATIVES
    NOSZAL, B
    KASSAITANCZOS, R
    NYIRI, J
    NYEKI, O
    SCHON, I
    INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1991, 38 (02): : 139 - 145
  • [26] Capillary electrophoretic studies of acid-base properties of sanguinarine and chelerythrine alkaloids
    Vlcková, M
    Barták, P
    Kubán, V
    JOURNAL OF CHROMATOGRAPHY A, 2004, 1040 (01) : 141 - 145
  • [27] Solubility and acid-base properties of concentrated phytate in self-medium and in NaClaq at T=298.15 K
    Cigala, Rosalia Maria
    Crea, Francesco
    Lando, Gabriele
    Milea, Demetrio
    Sammartano, Silvio
    JOURNAL OF CHEMICAL THERMODYNAMICS, 2010, 42 (11) : 1393 - 1399
  • [28] Acid-base dissociation and tautomerism of two aminofluorescein dyes in solution
    Mchedlov-Petrossyan, Nikolay O.
    Cheipesh, Tatyana A.
    Vodolazkaya, Natalya A.
    JOURNAL OF MOLECULAR LIQUIDS, 2017, 225 : 696 - 705
  • [29] Acid-base properties of phosphoric and acetic acid in aprotic organic solvents - A complete thermodynamic characterisation
    Barisic, D.
    Tomisic, V.
    Bregovic, N.
    ANALYTICA CHIMICA ACTA, 2019, 1046 : 77 - 92
  • [30] Predicting the Energetics of Hydrogen Intercalation in Metal Oxides Using Acid-Base Properties
    Miu, Evan, V
    Mpourmpakis, Giannis
    McKone, James R.
    ACS APPLIED MATERIALS & INTERFACES, 2020, 12 (40) : 44658 - 44670
12345