New oral anticoagulants - clinical applications

被引：0
作者：
Gallus, Alex [1 ,2 ]
机构：
[1] Flinders Univ S Australia, Adelaide, SA, Australia
[2] Flinders Med Ctr, SA Pathol, Adelaide, SA, Australia
来源：
AUSTRALIAN PRESCRIBER | 2010年 / 33卷 / 02期
关键词：
arthroplasty; dabigatran etexilate; rivaroxaban; thromboembolism; SYMPTOMATIC VENOUS THROMBOEMBOLISM; TOTAL KNEE ARTHROPLASTY; HEALTHY MALE-SUBJECTS; DABIGATRAN ETEXILATE; TOTAL HIP; THROMBIN INHIBITOR; RANDOMIZED-TRIAL; DOUBLE-BLIND; PREVENTION; ENOXAPARIN;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Rivaroxaban and dabigatran etexilate are oral anticoagulants that promise to be as effective as warfarin, but easier to use. The new drugs have shown similar or greater efficacy than low molecular weight heparins and comparable safety in the prevention of venous thromboembolism after hip or knee arthroplasty. Unlike other anticoagulants, routine monitoring is not required during short-term use. The drugs are also being assessed for other indications that include treatment of venous thromboembolism and preventing stroke in atrial fibrillation. Only the results of ongoing studies will tell if they can match warfarin and the heparins across their full range of clinical indications.
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页码：42 / 47
页数：6
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