One-pot synthesis of highly substituted imidazoles using molecular iodine: A versatile catalyst

被引：241

作者：

Kidwai, Mazaahir ^{[1
]}

Mothsra, Poonam

Bansal, Vikas

Somvanshi, Rishi K.

Ethayathulla, Abdul S.

Dey, Sharmistha

Singh, Tej P.

机构：

[1] Univ Delhi, Dept Chem, Green Chem Res Lab, New Delhi 110007, India

[2] All India Inst Med Sci, Dept Biophys, New Delhi 110029, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 265卷 / 1-2期

关键词：

2,4,5-trisubstituted imidazoles; 1,2,4,5-tetra substituted imidazoles; molecular iodine; TETRASUBSTITUTED IMIDAZOLES; EFFICIENT SYNTHESIS; PARALLEL SYNTHESIS; IONIC LIQUIDS; AMARYLLIDACEAE; SCELETIUM; THIAZOLE; OXAZOLE;

D O I：

10.1016/j.molcata.2006.10.009

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Molecular iodine has been used an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in excellent yields. The significant features of the iodine-catalyzed condensation are operational simplicity, inexpensive reagents, high yield of products and the use of non-toxic reagents. (c) 2006 Elsevier B.V All rights reserved.

引用

页码：177 / 182

页数：6

共 53 条

[1] Pyrimidinylimidazole inhibitors of p38: Cyclic N-1 imidazole substituents enhance p38 kinase inhibition and oral activity [J].

Adams, JL ;

Boehm, JC ;

Gallagher, TF ;

Kassis, S ;

Webb, EF ;

Hall, R ;

Sorenson, M ;

Garigipati, R ;

Griswold, DE ;

Lee, JC .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (21) :2867-2870

[2] A novel one-pot synthesis of tetrasubstituted imidazoles under solvent-free conditions and microwave irradiation [J].

Balalaie, S ;

Hashemi, MM ;

Akhbari, M .

TETRAHEDRON LETTERS, 2003, 44 (08) :1709-1711

[3] One-pot synthesis of tetrasubstituted imidazoles catalyzed by zeolite HY and silica gel under microwave irradiation [J].

Balalaie, S ;

Arabanian, A .

GREEN CHEMISTRY, 2000, 2 (06) :274-276

[4] Synthesis of chiral ionic liquids from natural amino acids [J].

Bao, WL ;

Wang, ZM ;

Li, YX .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (02) :591-593

[5] An efficient, high yield protocol for the one-pot synthesis of dihydropyrimidin-2(1H)-ones catalyzed by iodine [J].

Bhosale, RS ;

Bhosale, SV ;

Wang, TY ;

Zubaidha, PK .

TETRAHEDRON LETTERS, 2004, 45 (49) :9111-9113

[6] Parallel synthesis of substituted imidazoles from 1,2-aminoalcohols [J].

Bleicher, KH ;

Gerber, F ;

Wüthrich, Y ;

Alanine, A ;

Capretta, A .

TETRAHEDRON LETTERS, 2002, 43 (43) :7687-7690

[7] An efficient synthesis of tetrasubstituted imidazoles from N-(2-oxo)-amides [J].

Claiborne, CF ;

Liverton, NJ ;

Nguyen, KT .

TETRAHEDRON LETTERS, 1998, 39 (49) :8939-8942

[8]

CLARK NG, 1975, TETRAHEDRON LETT, P2717

[9] Parallel synthesis of 1,2,4-trisubstituted imidazoles via N-alkyl-N-(β-keto)amides using a carbazate linker [J].

Cobb, JM ;

Grimster, N ;

Khan, N ;

Lai, JYQ ;

Payne, HJ ;

Payne, LJ ;

Raynham, T ;

Taylor, J .

TETRAHEDRON LETTERS, 2002, 43 (42) :7557-7560

[10] Erosive-corrosive wear of aluminum alloy composites: Influence of slurry composition and speed [J].

Das, S. ;

Saraswathi, Y. L. ;

Mondal, D. P. .

WEAR, 2006, 261 (02) :180-190

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