Microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols

被引：6

作者：

Kim, Jeong Geun ^{[1
]}

Yang, Eun Hae ^{[2
]}

Youn, Woo Sup ^{[2
]}

Choi, Ji Won ^{[2
]}

Ha, Deok-Chan ^{[1
]}

Ha, Jae Du ^{[2
]}

机构：

[1] Korea Univ, Dept Chem, Seoul 136701, South Korea

[2] Korea Res Inst Chem Technol, Bioorgan Sci Div, Taejon 305600, South Korea

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 30期

关键词：

Microwave-assisted amination; 3-Bromo-2-chloropyridine; Aminoethanol; Pyrido[1,4]oxazine; ARYL CHLORIDES; BOND FORMATION; EFFICIENT; DESIGN; ANTAGONISTS; INHIBITORS; CATALYSTS; LIGANDS; POTENT;

D O I：

10.1016/j.tetlet.2010.05.021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple method for microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols is described. The reaction was carried out under microwave irradiation conditions (at 180 degrees C for 1-2 h) and the result was superior in terms of conversion and yield when compared to that of the corresponding conventional heating conditions. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：3886 / 3889

页数：4

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