Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective

被引：5

作者：

Kasibante, John ^{[1
]}

Rutakingirwa, Morris K. ^{[1
]}

Kagimu, Enock ^{[1
]}

Ssebambulidde, Kenneth ^{[1
]}

Ellis, Jayne ^{[1
,2
]}

Tugume, Lillian ^{[1
]}

Mpoza, Edward ^{[1
]}

Cresswell, Fiona ^{[2
,3
,4
]}

Meya, David B. ^{[1
,5
]}

机构：

[1] Makerere Univ, Infect Dis Inst, POB 22418, Kampala, Uganda

[2] London Sch Hyg & Trop Med, Clin Res Dept, Keppel St, London WC1E 7HT, England

[3] Med Res Council Uganda Virus Res Inst, Entebbe, Uganda

[4] London Sch Hyg & Trop Med, Uganda Res Unit, Entebbe, Uganda

[5] Makerere Univ, Coll Hlth Sci, Sch Med, Kampala, Uganda

来源：

JOURNAL OF CLINICAL TUBERCULOSIS AND OTHER MYCOBACTERIAL DISEASES | 2020年 / 20卷

关键词：

HIV; Cryptococcal meningitis; Tuberculosis; Tuberculosis preventive therapy; Cryptococcosis; AIDS; ANTIRETROVIRAL THERAPY; INFECTED ADULTS; HEPATOTOXICITY; RISK;

D O I：

10.1016/j.jctube.2020.100180

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated cryptococcal meningitis are severely immunocompromised and therefore should be eligible for TPT. In this commentary we discuss the challenges associated with starting tuberculosis preventive therapy in patients with HIV associated cryptococcal meningitis in a clinical setting, we highlight the benefit, existing gaps and research opportunities of tuberculosis preventive therapy in this patient population.

引用

页数：3

共 29 条

[1] Accuracy and incremental yield of urine Xpert MTB/RIF Ultra versus Determine TB-LAM for diagnosis of pulmonary tuberculosis [J].

Andama, A. ;

Jaganath, D. ;

Crowder, R. ;

Asege, L. ;

Nakaye, M. ;

Katumba, D. ;

Mwebe, S. ;

Semitala, F. ;

Worodria, W. ;

Joloba, M. ;

Mohanty, S. ;

Somoskovi, A. ;

Cattamanchi, A. .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2020, 96 (01)

[2]

Balcells ME, 2006, EMERG INFECT DIS, V12, P744

[3] Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis [J].

Boulware, David R. ;

Meya, David B. ;

Muzoora, Conrad ;

Rolfes, Melissa A. ;

Hullsiek, Katherine Huppler ;

Musubire, Abdu ;

Taseera, Kabanda ;

Nabeta, Henry W. ;

Schutz, Charlotte ;

Williams, Darlisha A. ;

Rajasingham, Radha ;

Rhein, Joshua ;

Thienemann, Friedrich ;

Lo, Melanie W. ;

Nielsen, Kirsten ;

Bergemann, Tracy L. ;

Kambugu, Andrew ;

Manabe, Yukari C. ;

Janoff, Edward N. ;

Bohjanen, Paul R. ;

Meintjes, Graeme .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (26) :2487-2498

[4] Cytokine-Mediated Systemic Adverse Drug Reactions in a Drug-Drug Interaction Study of Dolutegravir With Once-Weekly Isoniazid and Rifapentine [J].

Brooks, Kristina M. ;

George, Jomy M. ;

Pau, Alice K. ;

Rupert, Adam ;

Mehaffy, Carolina ;

De, Prithwiraj ;

Dobos, Karen M. ;

Kellogg, Anela ;

McLaughlin, Mary ;

McManus, Maryellen ;

Alfaro, Raul M. ;

Hadigan, Colleen ;

Kovacs, Joseph A. ;

Kumar, Parag .

CLINICAL INFECTIOUS DISEASES, 2018, 67 (02) :193-201

[5] Pulmonary cryptococcosis - Comparison of clinical and radiographic characteristics in immunocompetent and immunocompromised patients [J].

Chang, WC ;

Tzao, C ;

Hsu, HH ;

Lee, SC ;

Huang, KL ;

Tung, HJ ;

Chen, CY .

CHEST, 2006, 129 (02) :333-340

[6] Standardized Urine-Based Tuberculosis (TB) Screening With TB-Lipoarabinomannan and Xpert MTB/RIF Ultra in Ugandan Adults With Advanced Human Immunodeficiency Virus Disease and Suspected Meningitis [J].

Cresswell, Fiona V. ;

Ellis, Jayne ;

Kagimu, Enock ;

Bangdiwala, Ananta S. ;

Okirwoth, Michael ;

Mugumya, Gerald ;

Rutakingirwa, Morris ;

Kasibante, John ;

Quinn, Carson M. ;

Ssebambulidde, Kenneth ;

Rhein, Joshua ;

Nuwagira, Edwin ;

Tugume, Lillian ;

Martyn, Emily ;

Skipper, Caleb P. ;

Muzoora, Conrad ;

Grint, Daniel ;

Meya, David B. ;

Bahr, Nathan C. ;

Elliott, Alison M. ;

Boulware, David R. .

OPEN FORUM INFECTIOUS DISEASES, 2020, 7 (04)

[7] A Trial of Early Antiretrovirals and Isoniazid Preventive Therapy in Africa [J].

Danel, Christine ;

Moh, Raoul ;

Gabillard, Delphine ;

Badje, Anani ;

Le Carrou, Jerome ;

Ouassa, Timothee ;

Ouattara, Eric ;

Anzian, Amani ;

Ntakpe, Jean-Baptiste ;

Minga, Albert ;

Kouame, Gerard M. ;

Bouhoussou, Franck ;

Emieme, Arlette ;

Kouame, Antoine ;

Inwoley, Andre ;

Toni, Thomas-d'Aquin ;

Ahiboh, Hugues ;

Kabran, Mathieu ;

Rabe, Cyprien ;

Sidibe, Baba ;

Nzunetu, Gustave ;

Konan, Romuald ;

Gnokoro, Joachim ;

Gouesse, Patrice ;

Messou, Eugene ;

Dohoun, Lambert ;

Kamagate, Synali ;

Yao, Abo ;

Amon, Solange ;

Kouame, Amadou-Barenson ;

Koua, Aboli ;

Kouame, Emmanuel ;

Ndri, Yao ;

Ba-Gomis, Olivier ;

Daligou, Marcelle ;

Ackoundze, Simplice ;

Hawerlander, Denise ;

Ani, Alex ;

Dembele, Fassery ;

Guehi, Calixte ;

Kanga, Constance ;

Seri, Jonas ;

Oyebi, Mykayila ;

Mbakop, Nathalie ;

Makaila, Olewole ;

Babatunde, Carole ;

Babatounde, Nathanael ;

Bleoue, Gisele ;

Tchoutedjem, Mireille ;

Kouadio, Alain-Claude .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (09) :808-822

[8]

Dooley KE, 2020, C RETROVIRALS OPPORT

[9] Adverse events with isoniazid preventive therapy: experience from a large trial [J].

Grant, Alison D. ;

Mngadi, Kathryn T. ;

van Halsema, Clare L. ;

Luttig, Marietha M. ;

Fielding, Katherine L. ;

Churchyard, Gavin J. .

AIDS, 2010, 24 :S29-S36

[10] Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: a systematic review and meta-analysis [J].

Gupta, Rishi K. ;

Lucas, Sebastian B. ;

Fielding, Katherine L. ;

Lawn, Stephen D. .

AIDS, 2015, 29 (15) :1987-2002

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