Creating Collagen Nanowire Arrays by 'Bottom-Up' and 'Top-Down' Approaches on Mica Lattice Planes

被引：0

作者：

Li Li ^{[1
]}

Zhang Lei ^{[1
]}

Yang De-Liang ^{[1
]}

Sun Ming ^{[1
]}

Zeng Fan-Xi ^{[1
]}

Gu Wen-Hua ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Elect Engn & Optoelect Technol, Nanjing 210094, Jiangsu, Peoples R China

来源：

CHINESE JOURNAL OF INORGANIC CHEMISTRY | 2017年 / 33卷 / 05期

关键词：

collagen; bottom-up; top-down; nanowire; mesoscale; LIQUID-PHASE EPITAXY; ATOMIC-FORCE MICROSCOPY; GROWTH; PEPTIDES; CLOAK; DNA;

D O I：

10.11862/CJIC.2017.100

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

By using the mica (001) lattice plane as the substrate and rat tail type I collagen monomers as adsorbates, both 'bottom-up' self-assembly of protein monomers guided by the substrate and 'top-down' manipulation of protein membrane by AFM tip were investigated: (1) both preparation approaches can fabricate collagen nanowire arrays with precisely controllable structures; (2) the 'bottom-up' approach was due to the `reverse-phase biomineralization' mechanism arising from the cooperative recognition and regulation between the protein and substrate at the interface; (3) the 'top-down' manipulation was based on the 'molecular broom' mechanism of the AFM tip in the Contact Mode.

引用

页码：745 / 752

页数：8

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