Studies toward the synthesis of natural and unnatural dienediynes. Part 2: A practical approach to functionalised cyclopentenones

被引：28

作者：

Caddick, S ^{[1
]}

Khan, S

Frost, LM

Smith, NJ

Cheung, S

Pairaudeau, G

机构：

[1] Univ Sussex, Chem Lab, Ctr Biomol Design & Drug Dev, Brighton BN1 9QJ, E Sussex, England

[2] AstraZeneca Pharmaceut, Loughborough LE11 5RH, Leics, England

来源：

TETRAHEDRON | 2000年 / 56卷 / 45期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

cyclopentenones; diynes; isomerisation; pyrones; rearrangement;

D O I：

10.1016/S0040-4020(00)00846-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The dienediyne natural products contain a functionalised dihydroxylated cyclopentane motif. A critical evaluation of the methods for the preparation and rearrangements of pyranones to give 4,5-dihydroxylated cyclopentenones is presented. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8953 / 8958

页数：6

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