Recent advances in metal catalyzed intramolecular aryl additions-accessing bioactive molecules

被引：9

作者：

Burke, Anthony J. ^{[1
,2
]}

机构：

[1] Univ Evora, Sch Sci & Technol, Dept Chem, Rua Romao Ramalho 59, P-7000 Evora, Portugal

[2] Univ Evora, Ctr Quim Evora, Inst Res & Adv Training IIFA, Rua Romao Ramalho 59, P-7000 Evora, Portugal

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 11期

关键词：

Arylation; Catalysis; C-H activation; Boronic acids/esters; Enantioselectivity; Imines; NUCLEOPHILIC-ADDITION; ASYMMETRIC-SYNTHESIS; ARYLBORONIC ACIDS; ENANTIOSELECTIVE SYNTHESIS; ARYLATION; KETONES; CYCLIZATION; REDUCTION; ALDEHYDES; HYDROARYLATION;

D O I：

10.1016/j.tetlet.2016.02.023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Aminotetraline, 1-aminoindane, and benzocycloalkanol structures are privileged scaffolds demonstrating broad ranging pharmacological properties. In this review recent advances in the synthesis of molecules containing these scaffolds via metal catalyzed intramolecular aryl additions to activated groups like: imines, ketones, and aldehydes are discussed. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：1197 / 1204

页数：8

共 73 条

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