The role of estrogen in breast cancer

被引:9
作者
Khadem, Roaa [1 ]
Mahdi, Fatimah Chassab [2 ]
AI-Mosawi, Karrar [2 ]
AL-Janabi, Aliabdul Hussein S. [1 ]
机构
[1] Univ Karbala, Coll Med, Dept Microbiol, Karbala, Iraq
[2] Al Ammam Al Hussein Med City Hosp Karbala, Karbala, Iraq
来源
BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL | 2020年 / 4卷 / 04期
关键词
Breast cancer; estradiol; estrogen; estrogen receptor; RECEPTOR STATUS; RISK-FACTORS; MECHANISMS; WOMEN; ASSOCIATION; HISTORY; DISEASE;
D O I
10.4103/bbrj.bbrj_59_20
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Estrogen has a significant effect on the development of breast cancer. Its activities in the human body are mainly performed by binding to cellular estrogen receptor (ER). Breast cancer in relate to the presence of ER can be divided into ER-positive and ER-negative breast cancer. The role of estrogen and its receptors in the development of breast cancer will be discussed in this review.
引用
收藏
页码:293 / 296
页数:4
相关论文
共 49 条
[1]  
AL-Janabi AA, 2017, BRAZILIAN J MED HUM, V5, P134
[2]  
Althuis MD, 2004, CANCER EPIDEM BIOMAR, V13, P1558
[3]  
Alwan N. A. S., 2018, The Open Public Health Journal, V11, P177, DOI 10.2174/1874944501811010177
[4]  
Alwan N. A. S., 2010, Eastern Mediterranean Health Journal, V16, P1159
[5]  
Alwan NAS, 2019, J CONTEMP MED SCI, V5, P14
[6]  
American Cancer Society, 2020, CANC FACT FIGURE
[7]   Estrogen receptor breast cancer phenotypes in the surveillance, epidemiology, and end results database [J].
Anderson, WF ;
Chatterjee, N ;
Ershler, WB ;
Brawley, OW .
BREAST CANCER RESEARCH AND TREATMENT, 2002, 76 (01) :27-36
[8]   Poor prognosis of single hormone receptor-positive breast cancer: similar outcome as triple-negative breast cancer [J].
Bae, Soo Youn ;
Kim, Sangmin ;
Lee, Jun Ho ;
Lee, Hyun-chul ;
Lee, Se Kyung ;
Kil, Won Ho ;
Kim, Seok Won ;
Lee, Jeong Eon ;
Nam, Seok Jin .
BMC CANCER, 2015, 15
[9]  
Benz CC, 2003, CANCER EPIDEM BIOMAR, V12, P1523
[10]   Impact of aging on the biology of breast cancer [J].
Benz, Christopher C. .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2008, 66 (01) :65-74