Expression of Xenopus homologs of the β-catenin binding protein pontin52

被引：11

作者：

Etard, C

Wedlich, D

Bauer, A

Huber, C

Kühl, M

机构：

[1] Univ Ulm, Biochem Abt, D-89081 Ulm, Germany

[2] Max Planck Inst Immunbiol, Abt Mol Enbryol, D-79108 Freiburg, Germany

[3] Uniklin Benjamin Franklin, Inst Klin Chem, D-12200 Berlin, Germany

来源：

MECHANISMS OF DEVELOPMENT | 2000年 / 94卷 / 1-2期

关键词：

Xenopus; pontin52; reptin52; neural crest; adrenal medulla;

D O I：

10.1016/S0925-4773(00)00305-1

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Identification of pontin52 as an interaction partner of the Wnt/Wg signal transducer beta-catenin implicated a role for this protein in Wnt signaling. Here we describe the isolation of two Xenopus homologs of pontin52, Xpontin and Xreptin, and report the first expression pattern of vertebrate pontin52 homologs. Whole-mount in situ hybridization studies reveal a strong expression of Xpontin in neural crest cells and in later stages in different gastro;intestinal organs. Xreptin is also expressed in neural crest cells, in particular in a subpopulation that give raise to the adrenal medulla. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：219 / 222

页数：4

共 11 条

[1] Pontin52, an interacticon partner of β-catenin, binds to the TATA box binding protein [J].