Complexation of capsaicin with hydroxypropyl-β-cyclodextrin and its analytical application

被引：17

作者：

Huang, Zheng ^{[1
]}

Xu, Rui ^{[1
]}

Ge, Xia ^{[2
]}

Cheng, Jianxin ^{[2
]}

机构：

[1] Gansu Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Anim Husb Pasture & Green Agr Inst, Lanzhou 730070, Gansu, Peoples R China

[2] Gansu Acad Agr Sci, Inst Agr Prod Storage & Proc, Lanzhou 730070, Gansu, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 223卷

基金：

中国国家自然科学基金;

关键词：

Capsaicin; Hydroxypropyl-beta-cyclodextrin; Fluorospectrophotometry; Inclusion complex; Molecular modeling; INCLUSION COMPLEX; QUANTUM YIELDS; PEPPERS; DIHYDROCAPSAICIN; H-1-NMR; BINDING; SYSTEM;

D O I：

10.1016/j.saa.2019.117278

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Fluorescence spectra, H-1 NMR, thermoanalysis and molecular modeling were used to investigate the host-guest inclusion system of hydroxypropyl-beta-cydodextrin (HP beta CD) with capsaicin. Job's plot was employed to confirm a 1:2 host-guest stoichiometry. Phase solubility study indicated that the apparent stability constant was 3.76 x 10(6) M-2. With the enhancing fluorescence of capsaidn complexation with HP beta CD, a spectrofluorirnetric method approach to determine the capsaidn in bulk aqueous solution was developed. Linearity was achieved wide ranges (0.05-60 mu g/mL), with low detection limit of 0.04 mu g/mL, and the relative standard deviation was 1.30%. Application to the analysis of chili powder samples obtained a satisfactory recovery of 99.5-105.6%. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：7

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