Complexation of capsaicin with hydroxypropyl-β-cyclodextrin and its analytical application

被引：18
作者：
Huang, Zheng [1 ]
Xu, Rui [1 ]
Ge, Xia [2 ]
Cheng, Jianxin [2 ]
机构：
[1] Gansu Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Anim Husb Pasture & Green Agr Inst, Lanzhou 730070, Gansu, Peoples R China
[2] Gansu Acad Agr Sci, Inst Agr Prod Storage & Proc, Lanzhou 730070, Gansu, Peoples R China
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 223卷
基金：
中国国家自然科学基金;
关键词：
Capsaicin; Hydroxypropyl-beta-cyclodextrin; Fluorospectrophotometry; Inclusion complex; Molecular modeling; INCLUSION COMPLEX; QUANTUM YIELDS; PEPPERS; DIHYDROCAPSAICIN; H-1-NMR; BINDING; SYSTEM;
D O I：
10.1016/j.saa.2019.117278
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
Fluorescence spectra, H-1 NMR, thermoanalysis and molecular modeling were used to investigate the host-guest inclusion system of hydroxypropyl-beta-cydodextrin (HP beta CD) with capsaicin. Job's plot was employed to confirm a 1:2 host-guest stoichiometry. Phase solubility study indicated that the apparent stability constant was 3.76 x 10(6) M-2. With the enhancing fluorescence of capsaidn complexation with HP beta CD, a spectrofluorirnetric method approach to determine the capsaidn in bulk aqueous solution was developed. Linearity was achieved wide ranges (0.05-60 mu g/mL), with low detection limit of 0.04 mu g/mL, and the relative standard deviation was 1.30%. Application to the analysis of chili powder samples obtained a satisfactory recovery of 99.5-105.6%. (C) 2019 Elsevier B.V. All rights reserved.
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页数：7
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