Complexation of capsaicin with hydroxypropyl-β-cyclodextrin and its analytical application

被引：18

作者：

Huang, Zheng ^{[1
]}

Xu, Rui ^{[1
]}

Ge, Xia ^{[2
]}

Cheng, Jianxin ^{[2
]}

机构：

[1] Gansu Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Anim Husb Pasture & Green Agr Inst, Lanzhou 730070, Gansu, Peoples R China

[2] Gansu Acad Agr Sci, Inst Agr Prod Storage & Proc, Lanzhou 730070, Gansu, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 223卷

基金：

中国国家自然科学基金;

关键词：

Capsaicin; Hydroxypropyl-beta-cyclodextrin; Fluorospectrophotometry; Inclusion complex; Molecular modeling; INCLUSION COMPLEX; QUANTUM YIELDS; PEPPERS; DIHYDROCAPSAICIN; H-1-NMR; BINDING; SYSTEM;

D O I：

10.1016/j.saa.2019.117278

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Fluorescence spectra, H-1 NMR, thermoanalysis and molecular modeling were used to investigate the host-guest inclusion system of hydroxypropyl-beta-cydodextrin (HP beta CD) with capsaicin. Job's plot was employed to confirm a 1:2 host-guest stoichiometry. Phase solubility study indicated that the apparent stability constant was 3.76 x 10(6) M-2. With the enhancing fluorescence of capsaidn complexation with HP beta CD, a spectrofluorirnetric method approach to determine the capsaidn in bulk aqueous solution was developed. Linearity was achieved wide ranges (0.05-60 mu g/mL), with low detection limit of 0.04 mu g/mL, and the relative standard deviation was 1.30%. Application to the analysis of chili powder samples obtained a satisfactory recovery of 99.5-105.6%. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：7

共 37 条

[1]

Bajaj K.L., 1979, J MIKROCHIMICA ACTA, V71, P81

[2] Fast determination of capsaicinoids from peppers by high-performance liquid chromatography using a reversed phase monolithic column [J].

Barbero, G. F. ;

Liazid, A. ;

Palma, M. ;

Barroso, C. G. .

FOOD CHEMISTRY, 2008, 107 (03) :1276-1282

[3] Determination of Capsaicin and Dihydrocapsaicin in Some Chilli Varieties using Accelerated Solvent Extraction Associated with Solid-Phase Extraction Methods and RP-HPLC-Fluorescence [J].

Chanthai, Saksit ;

Juangsamoot, Jureerat ;

Ruangviriyachai, Chalerm ;

Techawongstien, Suchila .

E-JOURNAL OF CHEMISTRY, 2012, 9 (03) :1550-1561

[4] The antimicrobial properties of chile peppers (Capsicum species) and their uses in Mayan medicine [J].

Cichewicz, RH ;

Thorpe, PA .

JOURNAL OF ETHNOPHARMACOLOGY, 1996, 52 (02) :61-70

[5] Antioxidant and iron-binding properties of curcumin, capsaicin, and S-Allylcysteine reduce oxidative stress in rat brain homogenate [J].

Dairam, Amichand ;

Fogel, Ronen ;

Daya, Santy ;

Limson, Janice L. .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, 56 (09) :3350-3356

[6]

DEMAS JN, 1971, J PHYS CHEM-US, V75, P991, DOI 10.1021/j100678a001

[7] TOPICAL APPLICATION OF CAPSAICIN FOR TREATMENT OF ORAL NEUROPATHIC PAIN AND TRIGEMINAL NEURALGIA [J].

EPSTEIN, JB ;

MARCOE, JH .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1994, 77 (02) :135-140

[8] Hydroxypropyl-β-cyclodextrin enhanced fluorimetric method for the determination of melatonin and 5-methoxytryptamine [J].

Galian, RE ;

Veglia, AV ;

de Rossi, RH .

ANALYST, 2000, 125 (08) :1465-1470

[9]

Ganguly C, 2010, ASIAN PAC J CANCER P, V11, P25

[10] Determination of capsaicin and dihydrocapsaicin in Capsicum fruits by liquid chromatography-electrospray/time-of-flight mass spectrometry [J].

Garces-Claver, Ana ;

Arnedo-Andres, Maria S. ;

Abadia, Javier ;

Gil-Ortega, Ramiro ;

Alvarez-Fernandez, Ana .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (25) :9303-9311

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