The sparing use of fat: G0s2 controls lipolysis and fatty acid oxidation

被引：3
作者：
Heier, Christoph [1 ]
Zimmermann, Robert [1 ]
机构：
[1] Graz Univ, Inst Mol Biosci, A-8010 Graz, Austria
来源：
DIABETOLOGIA | 2015年 / 58卷 / 01期
基金：
奥地利科学基金会;
关键词：
Adipose triglyceride lipase; G(0)/G(1) switch gene 2; Insulin resistance; Lipolysis; Obesity; SWITCH GENE 2; ADIPOSE LIPOLYSIS; ENERGY-METABOLISM; MESSENGER-RNA; OVEREXPRESSION; PERILIPIN; PROTEIN; MICE; EXPRESSION;
D O I：
10.1007/s00125-014-3430-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：7 / 9
页数：3
相关论文
共 23 条
[1]   Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity [J].
Ahmadian, Maryam ;
Duncan, Robin E. ;
Varady, Krista A. ;
Frasson, Danubia ;
Hellerstein, Marc K. ;
Birkenfeld, Andreas L. ;
Samuel, Varman T. ;
Shulman, Gerald I. ;
Wang, Yuhui ;
Kang, Chulho ;
Sul, Hei Sook .
DIABETES, 2009, 58 (04) :855-866
[2]   Deletion of the gene encoding G0/G1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice [J].
El-Assaad, Wissal ;
El-Kouhen, Karim ;
Mohammad, Amro H. ;
Yang, Jieyi ;
Morita, Masahiro ;
Gamache, Isabelle ;
Mamer, Orval ;
Avizonis, Daina ;
Hermance, Nicole ;
Kersten, Sander ;
Tremblay, Michel L. ;
Kelliher, Michelle A. ;
Teodoro, Jose G. .
DIABETOLOGIA, 2015, 58 (01) :149-157
[3]   Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase [J].
Haemmerle, G ;
Lass, A ;
Zimmermann, R ;
Gorkiewicz, G ;
Meyer, C ;
Rozman, J ;
Heldmaier, G ;
Maier, R ;
Theussl, C ;
Eder, S ;
Kratky, D ;
Wagner, EF ;
Klingenspor, M ;
Hoefler, G ;
Zechner, R .
SCIENCE, 2006, 312 (5774) :734-737
[4]   Defective Adipose Lipolysis and Altered Global Energy Metabolism in Mice with Adipose Overexpression of the Lipolytic Inhibitor G0/G1 Switch Gene 2 (G0S2) [J].
Heckmann, Bradlee L. ;
Zhang, Xiaodong ;
Xie, Xitao ;
Saarinen, Alicia ;
Lu, Xin ;
Yang, Xingyuan ;
Liu, Jun .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (04) :1905-1916
[5]   The G0/G1 switch gene 2 (G0S2): Regulating metabolism and beyond [J].
Heckmann, Bradlee L. ;
Zhang, Xiaodong ;
Xie, Xitao ;
Liu, Jun .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2013, 1831 (02) :276-281
[6]   Adipose Triglyceride Lipase-Null Mice Are Resistant to High-Fat Diet-Induced Insulin Resistance Despite Reduced Energy Expenditure and Ectopic Lipid Accumulation [J].
Hoy, Andrew J. ;
Bruce, Clinton R. ;
Turpin, Sarah M. ;
Morris, Alexander J. ;
Febbraio, Mark A. ;
Watt, Matthew J. .
ENDOCRINOLOGY, 2011, 152 (01) :48-58
[7]   Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling [J].
Kienesberger, Petra C. ;
Lee, Daeho ;
Pulinilkunnil, Thomas ;
Brenner, Daniel S. ;
Cai, Lingzhi ;
Magnes, Christoph ;
Koefeler, Harald C. ;
Streith, Ingo E. ;
Rechberger, Gerald N. ;
Haemmerle, Guenter ;
Flier, Jeffrey S. ;
Zechner, Rudolf ;
Kim, Young-Bum ;
Kershaw, Erin E. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (44) :30218-30229
[8]   Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation [J].
Kioka, Hidetaka ;
Kato, Hisakazu ;
Fujikawa, Makoto ;
Tsukamoto, Osamu ;
Suzuki, Toshiharu ;
Imamura, Hiromi ;
Nakano, Atsushi ;
Higo, Shuichiro ;
Yamazaki, Satoru ;
Matsuzaki, Takashi ;
Takafuji, Kazuaki ;
Asanuma, Hiroshi ;
Asakura, Masanori ;
Minamino, Tetsuo ;
Shintani, Yasunori ;
Yoshida, Masasuke ;
Noji, Hiroyuki ;
Kitakaze, Masafumi ;
Komuro, Issei ;
Asano, Yoshihiro ;
Takashima, Seiji .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (01) :273-278
[9]   Human Congenital Perilipin Deficiency and Insulin Resistance [J].
Kozusko, Kristina ;
Patel, Satish ;
Savage, David B. .
HORMONE RESISTANCE AND HYPERSENSITIVITY: FROM GENETICS TO CLINICAL MANAGEMENT, 2013, 24 :150-+
[10]   Lipolysis - A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores [J].
Lass, Achim ;
Zimmermann, Robert ;
Oberer, Monika ;
Zechner, Rudolf .
PROGRESS IN LIPID RESEARCH, 2011, 50 (01) :14-27
123