Endemic prevalence of hepatitis B and C in Mongolia: A nationwide survey amongst Mongolian adults

被引:30
作者
Dashtseren, B. [1 ,2 ,3 ]
Bungert, A. [1 ]
Bat-Ulzii, P. [1 ,2 ]
Enkhbat, M. [1 ,2 ]
Lkhagva-Ochir, O. [1 ,2 ]
Jargalsaikhan, G. [1 ,2 ]
Enkhbat, A. [1 ,2 ]
Oidovsambuu, O. [1 ,2 ,4 ]
Klemen, J. [1 ]
Dashdorj, N. [1 ,2 ]
Dashdorj, N. [1 ,2 ]
Genden, Z. [1 ,2 ]
Yagaanbuyant, D. [1 ,2 ,3 ]
机构
[1] Onom Fdn, Ulaanbaatar, Mongolia
[2] Liver Ctr, Ulaanbaatar, Mongolia
[3] Mongolian Natl Univ Med Sci, Ulaanbaatar, Mongolia
[4] Natl Univ Mongolia, Ulaanbaatar, Mongolia
关键词
HBV; HCV; Mongolia; prevalence; risk factors; APPARENTLY HEALTHY-INDIVIDUALS; DELTA-VIRUS INFECTIONS; HEPATOCELLULAR-CARCINOMA; GENOTYPE DISTRIBUTION; GLOBAL PREVALENCE; CHILDREN; ODDS;
D O I
10.1111/jvh.12697
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In this study, a representative group of Mongolian adults was tested for hepatitis B virus (HBV) and hepatitis C virus (HCV). Screening was conducted at 17 different locations on a randomly sampled group, representing the Mongolian adult population. A total of 1158 adults, 500 (43.1%) men and 659 (56.9%) women were included. The prevalence estimates of HBV and HCV amongst the general Mongolian adult population were found to be 11.1%+/- 1% (SE) and 8.5%+/- 0.7% or 207418 and 160228 cases, respectively. For HCV, the majority of cases are concentrated in older age groups with a prevalence of 25.8% amongst those aged 50years and above, whilst the prevalence of HBV does not vary significantly amongst age groups. For both, HBV and HCV, the data indicate a higher risk of infection and a higher mortality because of the hepatitis amongst men than amongst women. This study represents the first nationwide estimate of the prevalence of HBV in Mongolia and also considered the first for HCV since 2005 and confirm the position of Mongolia as one of the hot-spots of chronic hepatitis infection in the world with about 19.4% of the adult population being infected with either HBV or HCV.
引用
收藏
页码:759 / 767
页数:9
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