Undetectable viral RNA in oocytes from SARS-CoV-2 positive women

被引：56

作者：

Barragan, M. ^{[1
]}

Guillen, J. J. ^{[1
]}

Martin-Palomino, N. ^{[1
]}

Rodriguez, A. ^{[1
]}

Vassena, R. ^{[1
]}

机构：

[1] Clin EUGIN, Carrer Balmes 236, Barcelona 08006, Spain

来源：

HUMAN REPRODUCTION | 2021年 / 36卷 / 02期

关键词：

coronavirus; COVID-19; oocyte; SARS-CoV-2; IVF; ICSI; ovarian stimulation; EXPRESSION; TMPRSS2; ACE2;

D O I：

10.1093/humrep/deaa284

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A central concern for the safe provision of ART during the current coronavirus disease 2019 (COVID-19) pandemic is the possibility of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through gametes and preimplantation embryos. Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected individuals are not available to date. We describe the case of two women who underwent controlled ovarian stimulation and tested positive to SARS-CoV-2 infection by PCR on the day of oocyte collection. The viral RNA for gene N was undetectable in all the oocytes analyzed from the two women.

引用

页码：390 / 394

页数：5

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