The genetic diversity of Plasmodium vivax -: A review

被引：27
作者：
Christina de Souza-Neiras, Wanessa [1 ]
Storti de Melo, Luciane Moreno
Dantas Machado, Ricardo Luiz
机构：
[1] Univ Estadual Paulista, Dept Biol, Inst Biociencias Letras & Ciencias Exatas, Sao Jose Do Rio Preto, SP, Brazil
[2] Fac Med Sao Jose Rio Preto, Ctr Invest Microorganismos, Dept Doencas Dermatol Infecciosas & Parasitarias, BR-15090000 Sao Jose Do Rio Preto, SP, Brazil
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2007年 / 102卷 / 03期
关键词：
malaria; Plasmodium vivax; genetic diversity; molecular markers; phylogeny; evolution;
D O I：
10.1590/S0074-02762007000300002
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
引用
收藏
页码：245 / 254
页数：10
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